Cerebrospinal Fluid

(redirected from Cerebral Spinal Fluid)
Also found in: Dictionary, Thesaurus, Medical.
Related to Cerebral Spinal Fluid: choroid plexus, lumbar puncture

cerebrospinal fluid

[sə¦rē·brō′spīn·əl ′flü·əd]
(physiology)
A clear liquid that fills the ventricles of the brain and the spaces between the arachnoid mater and pia mater.

Cerebrospinal Fluid

 

the liquid that circulates in the ventricles of the brain and spinal canal and in the subarachnoid space (under the arachnoidea) of the brain and spinal cord. Cerebrospinal fluid is formed by vascular plexuses, glandular cells, the epen-dyma and subependymal tissue of the ventricles of the brain, the arachnoidea, and the glia. Drainage is through the venous plexuses of the brain, sinuses of the dura mater, and the perineural spaces of the cranial and spinal nerves.

Cerebrospinal fluid serves as a water cushion that protects the brain and spinal cord from external forces. It regulates intracranial pressure and ensures the constancy of the internal medium. Tissue metabolism in the central nervous system is achieved through cerebrospinal fluid. In a healthy individual, the fluid is transparent and colorless. Adults have 100–150 milliliters of cerebrospinal fluid, which varies in specific weight from 1.006 to 1.007. The fluid is slightly alkaline, and its pressure varies at different levels of the central nervous system, depending on the position of the body. (Cerebrospinal pressure is 100–200 mm H2O in the horizontal position.) In its chemical composition, cerebrospinal fluid is similar to blood serum. It may contain from zero to five cells per cu mm and 0.22-.33 parts per thousand protein.

The diagnosis and treatment of various conditions is facilitated by lumbar puncture, which permits cerebrospinal pressure to be measured and the fluid to be extracted for analysis purposes. Damage to the central nervous system alters the pressure and composition (especially the ratio between proteins and cells) of cerebrospinal fluid. Cerebrospinal pressure increases in cases of drainage disorders, which may be caused by traumas of the skull and spine, brain tumors, and hemorrhages. Bacteria are found in the fluid during meningitis. Lange’s test and the benzoin test are used in diagnosing syphilis. The biochemical analysis of the sugar, chlorides, free amino acids, and enzymes contained in cerebrospinal fluid is useful in the determination of neuroinfections and epilepsy.

REFERENCES

Shamburov, D. A. Spinnomozgovaia zhidkost’. Moscow, 1954.
Burgman, G. P., and T. N. Lobkova. Issledovanie spinnomozgovoi zhidkosti. Moscow, 1968.
Makarov, A. Iu. Sovremennye biokhimicheskie issledovaniia likvora v nevrologii. Leningrad, 1973.

V. B. GELFAND

References in periodicals archive ?
Her theory was that our son crashed because he blacked out due to the colloid cyst and that he had hydrocephalus before he crashed, and she was determined to install two tubes, called shunts, permanently into our son's brain, one on the left side and one on the right side, which would be implanted beneath the skin behind the ears, go through the neck and down into his abdominal cavity for draining cerebral spinal fluid from his brain.
The ventricular catheter is the preferred device for monitoring ICE Advantages include low cost and the ability to drain cerebral spinal fluid CSF to reduce ICP.
The research team found that a decrease in the content of mitochondrial DNA (mtDNA) in the cerebral spinal fluid may indicate Alzheimer's and could also play a role in cause the disease.
As Jackson's condition worsened, Fine explains, the blood blocked the flow of Jackson's cerebral spinal fluid, which in turn created a second problem called hydrocephalus, an abnormal accumulation of cerebral spinal fluid in the brain's ventricles.
The youngster suffers from Holoprosencephaly, a major defect of brain formation where, instead of normal brain tissue, the skull is swelled with extra cerebral spinal fluid.
It is usually caused by a bacterial or viral infection that invades the cerebral spinal fluid (CSF), the fluid that protects and cushions the brain and spinal cord.
Among these strains, 13% (n = 6) were isolated from upper-respiratory-tract infections, 60% (n = 27) from lower-respiratory-tract infections, 11% (n = 5) from cerebral spinal fluid, 7% (n = 3) from blood culture, 7% (n = 3) from eye infections and 2% (n = 1) from sinovial fluid (Table 1).
At high concentrations hCG can be detected in serum, but measurement of hCG concentrations in cerebral spinal fluid (CSF) is a more sensitive and reliable indicator of tumor presence (1).
A spinal tap showed that the cerebral spinal fluid (CSF) had a high protein level (148 mg/dL) and a low glucose level (15 mg/dL).
He was born with too much cerebral spinal fluid in his skull.
Literature distributed by the Wisconsin HBOT Center explains that "HBOT allows the body to incorporate more oxygen into blood cells, blood plasma, cerebral spinal fluid, and other bodily fluids.
Itzhaki's laboratory demonstrated that HSV-1 DNA is present in brain tissue and that antibodies to the virus can be found in the cerebral spinal fluid in a high proportion of patients with Alzheimer's disease (AD) and elderly patients who do not show signs of the disease (J.