Chagas Disease

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Chagas’ Disease


(also called American trypanosomiasis), a transmissible parasitic disease of humans and animals caused by trypanosomes. The disease was described in 1909 in Brazil (state of Minas Gerais) by the physician C. Chagas. It occurs in Central and South America, chiefly among the poorest strata of the population, who live in dwellings infested by transmitters of the disease (bloodsucking hemipterous insects, mainly triatomids). Humans and wild and domestic animals suffering from Chagas’ disease are the sources of infection.

Infection occurs when the causative agent, together with insect feces, enters injured skin or the mucous membranes of the eyes, nose, and mouth. The main symptoms are fever and enlargement of the lymph nodes in the acute stage, with involvement of the heart and gastrointestinal tract when the disease becomes chronic. The main methods for controlling Chagas’ disease are improvement of social and living conditions of the people, disinsectization, and destruction of infected animals.

References in periodicals archive ?
Author John Trumble responds: I considered including Chagas disease because, according to the National Institutes of Health, the United States has about 500,000 people infected with the trypanosome.
Em cerca de 10% dos casos de doenca de Chagas ha alguma alteracao neurologica, sendo os quadros mais graves em criancas abaixo de dois anos de idade e individuos em imunossupressao pela sindrome da imunodeficiencia adquirida (AIDS) ou em tratamento para transplante de orgaos (PRATA, 1994).
tests for the early detection of diseases and personalized health management, announced it has been granted United States Patent 7,473,528 entitled "Method for the detection of Chagas disease related gene transcripts in blood".
Having missed out on the opportunity to represent their birth nation, Christine Santanna and Andrezza Chagas took up the invitation of the Georgian president's wife, herself a keen beach volleyball player and fan.
Preliminary research on about 60 Chagas patients indicates that injecting their own bone marrow into the bloodstream may improve heart function and stamina.
New human and animal cases of Chagas disease have infectious disease experts on alert in the United States, where the parasite that causes the disease is being reported in increasing numbers.
Francisco das Chagas Rodrigues de Brito, a 41-year- old bike mechanic, was given 19 years for homicide and one year and eight months for hiding the body of the 15-year-old victim.
According to Doctors Without Borders, just 13 out of 1,233 new medicines marketed by major drug companies between 1975 and 1997 were designed to treat tropical parasitic illnesses such as malaria, Chagas disease--the leading cause of heart disease in Latin America, one which claims 50,000 people each year--and leishmaniasis, a fatal disease transmitted by sandflies.
We believe this case provides another example of masters and officers becoming a convenient scapegoat for an accident in the absence of other accessible parties and has highlighted once again the need for internationally-agreed measures to protect seafarers from unjust criminalisation", said Mr Chagas.
Scientists say the DNA map could help researchers develop a new drug to fight maladies like leishmaniasis and Chagas disease.
In chapter 12 the pig tapeworm and Chagas disease, both of which have reached the United States with Latin American immigrants, become today's examples of yesterday's phenomenon of pathogens traveling in the blood and bowels and on the breath of the European and African immigrants, which the author earlier implied, wiped out 90 percent of the native American population.