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Related to Chemotactic factors: histamine, chemotaxin


see taxistaxis
, movement of animals either toward or away from a stimulus, such as light (phototaxis), heat (thermotaxis), chemicals (chemotaxis), gravity (geotaxis), and touch (thigmotaxis). The turning movements of plants in response to stimuli are called tropisms.
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the movement of cells (zoospores, spermatozoids, leukocytes) and freely moving plants and protozoans in response to chemical stimuli. Positive chemotaxis is movement toward the source of the chemical stimulus (along the chemical concentration gradient in air or water); negative chemotaxis is movement away from the source. The phenomenon is known to exist in a number of microorganisms and invertebrates. The movement of insects in response to pheromones may also be regarded as chemotaxis.

The substances that induce chemotaxis vary from organism to organism. For example, cyclic adenosine monophosphate is an aggregating substance for soil myxomycetes of the genus Dictyostelium. Female sexual cells of the aquatic fungus Allomyces release the isoprenoid syrenin, a stimulus of chemotaxis of male sexual cells toward female cells. The mechanism by which a chemical signal is sensed (chemoreception) and the pathway to the corresponding physiological reaction, that is, oriented movement, are not thoroughly understood. Chemotaxis plays a part in the search for food, in fertilization in higher plants and animals, and in phagocytosis.


Behaviour of Microorganisms. London-New York, 1973.
Chemotaxis: Its Biology and Biochemistry. Edited by E. Sorkin. Basel, 1974.


The orientation or movement of a motile organism with reference to a chemical agent.
References in periodicals archive ?
Stromal cell-derived factor 1 is secreted by meningeal cells and acts as chemotactic factor on neuronal stem cells of the cerebellar external granular layer.
In the inflammatory responses, the circulating monocytes influx are mediated by different chemotactic factors as the protein-1 (MCP-1), and in the inflammatory focus differentiate into exudates macrophage (Bodel et al.
Some of these were present in more than 3 samples: growth factors (fibroblast growth factor 4, placental growth factor), chemotactic factors [B lymphocyte chemoattractant/CXCL13, macrophage inflammatory protein (MIP)-1[beta]/CCL4, MIP-1[delta]/ CCL15, MIP-3[alpha]/CCL20, pulmonary and activation-related chemokine (PARC)/CCL18, leukemia inhibitory factor, oncostatin M], and antiinflammatory factors [tissue inhibitor of metalloproteinase (TIMP)-1, TIMP-2, macrophage-derived chemokine (MDC)/CCL22].
Chemotactic factors presumably modulate the influx of eosinophils, one of which is histamine.
Once LDL-C has passed through the endothelium into the subendothelial space due to enhanced lipid permeability, oxidation of LDL-C occurs and a number of chemotactic factors are also released.
It also inhibits the release of chemotactic factors reducing the migration of neutrophils into the joint.
Tokyo, Japan) has patented leukocyte chemotactic factors such as interleukin-8 and MCAF, and inductive substances therefor having proconceptive activities.
The disintegrating tunic cells may release chemotactic factors that induce blood cell infiltration.
During the study, we found that the humanized monoclonal antibody MORAb-004 was able to specifically bind to a region of endosialin/TEM1 and inhibit endosialin/TEM1-ECP interactions that in turn resulted in suppressed cell migration to chemotactic factors," said Luigi Grasso, Ph.
They act as reservoirs of inflammatory mediators and rapidly synthesise others on activation like histamine, proteases, chemotactic factors and metabolites of arachidonic acid.
The role of MPO in the regulation of the course of pulmonary inflammation, independent of its putative microbicidal functions, can be potentially linked to its ability to modulate the life span of neutrophils and affect accumulation of chemotactic factors at the site of inflammation.
As such, it is possible that the relative ability of the CRP concentrations and eosinopenia in diagnosing different types of sepsis is different, depending on the severity of systemic inflammation and amount of chemotactic factors released into the systemic circulation.