Chemotherapeutic Agent


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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Chemotherapeutic Agent

 

the name given to various groups of drugs used in chemotherapy and chemoprophylaxis. Chemotherapeutic agents include substances of natural origin (for example, antibiotics) and synthetic preparations (for example, sulfanilamides, nitrofurans, and para-aminosalicylic acid). Antimicrobial, antiparasitic, and antineoplastic chemotherapeutic agents are distinguished. With the discovery and use of sulfanilamides (G. Domagk) and antibiotics (A. Fleming, H. Florey, and E. Chain) in the 1930’s and 1940’s, chemotherapeutic agents became the principal means of treating infectious diseases. In the 1940’s and 1950’s nitrogen mustard and many other agents became important in the treatment of malignant tumors.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
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The chemical involved contained nitrogen, and it occurred to Ehrlich that if the similar but much more poisonous element arsenic were substituted for the nitrogen, it might prove a more effective chemotherapeutic agent.
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(Calgary, Canada) has been granted Canadian Patent 2,437,468 entitled "Sensitization of Chemotherapeutic Agent Resistant Neoplastic Cells with Reovirus." The claims describe using a combination of reovirus and chemotherapy to treat cancer patients, and particularly those who are resistant to or may develop resistance to chemotherapeutic treatments.
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