chenodeoxycholic acid


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chenodeoxycholic acid

[¦kē·nō‚dē‚äk·sē¦kō·lik ′as·əd]
(biochemistry)
C24H40O4 A constituent of bile; needlelike crystals with a melting point of 119°C; soluble in alcohol, methanol, and acetic acid; used on an experimental basis to prevent and dissolve gallstones. Also known as anthropodesoxycholic acid; chenic acid; gallodesoxycholic acid.
References in periodicals archive ?
The 4 major bile acids, lithocolic acid, cholic acid, deoxycholic acid and chenodeoxycholic acid (all supplied by Sigma Aldrich, SA) were selected for study.
Ursodeoxycholic acid alone or with chenodeoxycholic acid for dissolution of cholesterol gallstones: A randomized multicenter trial.
TREATMENT with drugs such as chenodeoxycholic acid or urodeoxycholic acid can slowly dissolve the stones, but may cause side effects such as diarrhoea.
The strange thing is, when you get gallstones now in this great country of America, you're often given a drug called chenodeoxycholic acid.
Short of surgery, the only gallstone therapy currently approved in the United States is treatment with chenodeoxycholic acid.