Chlorogenic Acid

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chlorogenic acid

[¦klȯr·ə¦jen·ik ′as·əd]
C16H18O9 An important factor in plant metabolism; isolated from green coffee beans; the hemihydrate crystallizes in needlelike crystals from water.

Chlorogenic Acid


C16H18O9, a complex ester of caffeic acid with one of the stereoisomers of quinic acid. It is obtained in the form of colorless crystals, which have a melting point of 206°–210°C and are readily soluble in water. Alkaline solutions of chlorogenic acid turn green in the air (hence the name). It is very common among the higher plants, frequently occurring together with its isomer isochlorogenic acid. It is contained in large quantities in germinating sunflower seeds and in green coffee beans. Chlorogenic acid probably plays a part in regulating the ripening of fruits by acting on the respiration of the fruits as an inhibitor of oxidative phosphorylation. It is toxic to some pathogenic microorganisms that cause a number of plant diseases, such as potato scab and wilt disease. In a number of plants, for example, rice, the biosynthesis of chlorogenic acid increases in response to a microbial infection.

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The compound chlorogenic acid also helps reduce insulin resistance.
Effects of chlorogenic acid on voltage-gated potassium channels of trigeminal ganglion neurons in an inflammatory environment.
DPPH (2,2-diphenyl-l-picrylhydrazyl), ABTS (2,2'-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid), Folin-Ciocalteu (FC) reagent, capsaicin, dihydrocapsaicin myricetin, catechin, resveratrol, gallic acid, coumaric acid, caffeic acid, ferulic acid, sinapic acid, and chlorogenic acid were purchased from Sigma-Aldrich (St.
This coffee contains chlorogenic acid, which is popularly known as metabolism booster.
The plant contains xanthine alkaloids, saponins, chlorogenic acid, vitamins and 15 amino acids.
Tart Cherry contains polyphenols with antioxidant capabilities: anthocyanins, catechins, and chlorogenic acid.
Green coffee beans are coffee beans that have not yet been roasted, resulting in a higher level of chlorogenic acid compared with roasted coffee beans.
Berberine effects have also been studied when associated with chlorogenic acid and tocotrienols.
Phenolic compounds such as flavonoids and chlorogenic acid are considered to be the major contributors to the antioxidant ability of plants (Ong et al.
uk, said: "Coffee contains chlorogenic acid and caffeic acid, which have antioxidant properties that may help reduce inflammation and protect against chronic disease.
Strong antioxidants chlorogenic acid (CLA) which is found in the coffee bean.
Regulation mechanism of chlorogenic acid synthesis during the floral organ development of Lonicera confusa was investigated.