myasthenic crisis

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myasthenic crisis

[¦mī·əs¦thēn·ik ′krī·səs]
(medicine)
Profound myasthenia and respiratory paralysis associated with myasthenia gravis.
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Acute cholinergic crisis and respiratory failure, such as Intermediate Syndrome are frequently related to death.
The effects of muscarinic stimulation end up with cholinergic crisis.
initial life-threatening acute cholinergic crisis, which often requires management in intensive care unit.
The major challenge is to distinguish myasthenic from cholinergic crisis because both are characterized by muscle weakness and respiratory distress.
She was admitted with signs and symptoms of cholinergic crisis.
Type II Paralysis or Intermediate Syndrome: It follows the intense cholinergic crisis of organophosphorus poisoning and occurs in up 20%-50% of cases depending on the severity of poisoning, its duration, and on the type of organophosphorus compound.
The commonest presentation is the acute cholinergic crisis, usually diarrhoea, urinary frequency, miosis, bradycardia, bronchorrhoea and bronchoconstriction, emesis, lacrimation, salivation (easily remembered by the mnemonic DUMBELS) and hypotension.
Following prescribed, optimal dosage recommendations is very important as toxic amounts of CHE inhibitors may cause a cholinergic crisis, resulting in muscle weakness and possible respiratory collapse.
A cholinergic crisis, together with reduced levels of plasma BuChE activity, leads to the diagnosis of overcholinergic syndrome (Martin-Rubi et al.