Chorionic Gonadotropin

Also found in: Dictionary, Thesaurus, Medical, Financial, Wikipedia.

chorionic gonadotropin

[‚kȯr·ē′än·ik gō‚nad·ə′trō·pən]

Chorionic Gonadotropin


a hormone produced by the villi of the chorion and the placenta in some of the higher apes and in man. It is a complex protein (glycoprotein) containing the carbohydrates galactose (10.7 percent) and hexosamine (5.2 percent) and having a molecular weight of approximately 100,000. Chorionic gonadotropin has a stimulating effect on the corpus luteum, causing it to grow in size, increasing its secretory activity and prolonging its life; it converts the corpus luteum into the corpus luteum of pregnancy, which continues to secrete the hormone progesterone until the placenta is fully formed.

Chorionic gonadotropin, while similar in effect to the luteinizing hormone of the pituitary, differs from it in certain respects: it does not restore gonads atrophied after removal of the pituitary, it has no effect on avian gonads, and it causes only a slight enlargement of the ovaries in immature rodents.

References in periodicals archive ?
Doubling times of human chorionic gonadotropin increase in early viable intrauterine pregnancies.
Evaluation of Clinitest[R] hCG device susceptibility to high-dose hook effect by intact human chorionic gonadotropin (hCG) and hCG beta-core fragment at concentrations observed in early natural pregnancy [Abstract].
Serial beta-subunit human chorionic gonadotropin doubling time as a prognosticator of pregnancy outcome in an infertile population.
Evidence for the presence of human chorionic gonadotropin (hCG) and free beta-subunit of hCG in the human pituitary.
Radioimmunoassay: a method for human chorionic gonadotropin and human luteinizing hormone.
Sofia is intended for use on the Sofia Analyzer for the detection of increased levels of human chorionic gonadotropin (hCG), an indicator of pregnancy.
The injection is to be used for weight loss as an alternative to the human chorionic gonadotropin (HCG) diet.
The human chorionic gonadotropin (hCG) discriminatory zone--the maternal serum [beta]-hCG range above which a gestational sac should be consistently visible by ultrasonography (US) in a normal pregnancy--should not be used to determine the management of a hemodynamically stable patient who is suspected of having an ectopic pregnancy, according to this retrospective study.
The RapidVue hCG test is a lateral-flow pregnancy immunoassay for the qualitative detection of human chorionic gonadotropin (hCG).
Lead researcher Dr Johana Vanegas showed that presence of human chorionic gonadotropin (hCG), a hormone produced by the placenta to maintain the early stages of pregnancy offers protection against breast cancer.
They can choose first-trimester combined screening, in which nuchal translucency (NT), pregnancy-associated plasma protein A (PAPP-A), and free [beta]-human chorionic gonadotropin (hCG) are measured at 10-14 weeks and the results are provided.
The medical establishment view became that HCG - or human chorionic gonadotropin, a hormone extracted from the urine of pregnant women - was useful for treating infertility in women but had not been demonstrated as effective against obesity.

Full browser ?