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(cell and molecular biology)
The initial stage of mitotic or meiotic cell division in which chromosomes are condensed from the nuclear material and split logitudinally to form pairs.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



one of the stages of mitotic cell division. During prophase of mitosis, the mitotic apparatus is formed and the chromosomes, which already consist of two sister chromatids, spiralize. In most cells, the nuclear membrane fragmentizes and the nucleolus is destroyed during prophase.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Predictive value of sperm chromatin condensation (aniline blue staining) in the assessment of male fertility.
Macrocephaly in bull spermatozoa is associated with nuclear vacuoles; diploidy and alteration of chromatin condensation. Cytogenet.
(B) illustrates chromatin condensation and fragmentation (arrows), (B)(i) untreated (8000x), (B)(ii) 10 [micro]M Cisplatin treated cells for 4h (6000x), (B)(iii) 10 Carboplatin treated cells for 2h (8000x), and (B)(iv) 10 [micro]M Oxaliplatin treated cell for 4 h (10000x).
(13) Accordingly, we enquired the effect of zerumbone on Leishmania chromatin condensation and nuclear blebbing, the hallmark of apoptosis.
In conclusion, ROT-induced apoptosis proceeds in a domino-like mechanism triggered by [O.sub.2.sup.*-]/[H.sub.2][O.sub.2], which in turn activates ([much greater than]) kinases > NF-[kappa]B, JNK (>c-Jun) > p53 [much greater than] [DELTA][[PSI].sub.m] > caspase-3, AIF > chromatin condensation (stage I), and nuclei fragmentation (stage II).
Dadoune JR Use of the acridine orange staining on smears of human spermatozoa after heat-treatment: evaluation of the chromatin condensation. Andrologia 1989;21:275-80.
Spermiogenic nuclear protein transitions and chromatin condensation. Proposal for an ancestral model of nuclear spermiogenesis.
Morphological changes in apoptosis are chromatin condensation and nuclear fragmentation.
* Apoptosis--Stage II chromatin condensation into compact figures, which are often globular or crescent shaped.
The apoptotic features noted included, chromatin condensation (white arrows-Figure 3), nuclear pyknosis (white arrowheads-Figure 3) and nuclear fragmentation (bottom panels-Figure 3).
Slides were observed under UV-fluorescence microscope within 30 min before the fluorescent color faded accordingly: (i) viable cells appeared to have green nucleus with intact structure; (ii) early apoptotic cells exhibited a bright-green nucleus showing condensation of chromatin in the nucleus; (iii) dense orange areas of chromatin condensation revealed late apoptosis, and (iv) orange intact nucleus depicted secondary necrosis.
In mammalian cells, phosphorylation of the Serine 10 residue of histone H3 is negligible during interphase but reaches a maximum for chromatin condensation during mitosis.