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Hives or nettle rash; a skin condition characterized by the appearance of intensely itching wheals or welts with elevated, usually white centers and a surrounding area of erythema. Also known as hives.



nettle rash, an allergic reaction characterized by the sudden and rapid appearance on the skin (sometimes also on the laryngeal mucosa) of intensely itching wheals.

Urticaria is often caused by the sting of the nettle and certain other plants. Insect bites, temperature, and chemical agents are also among its causes. Other factors include parasitic worms, chronic constipation, liver and kidney diseases, and allergic sensitivity to some foods (for example, strawberries, citrus fruits, eggs, mushrooms, preserves, certain fish, pork, and chocolate). Urticaria is sometimes caused by hypersensitivity to drugs (especially to those of chemical origin). The rash associated with the condition is a manifestation of the inflammatory reaction and edema of the skin that result from a sudden increase in the permeability of the capillaries in the area. This results from the liberation of histamine from the mast cells of the skin by allergic alteration. Urticaria usually disappears without a trace within a few hours, although it sometimes recurs. It is treated by purgation (by enemas, laxatives), special diet (mostly milk and vegetables, with limited salt intake), and desensitizing and anti-histaminic agents.


Pavlov, S. T. Kozhnye i venericheskie bolezni, 2nd ed. Moscow, 1969.


References in periodicals archive ?
Dermal mast cell activation by autoantibodies against the high affinity IgE receptor in chronic urticaria.
It has been reported that the risk of chronic urticaria increases in individuals who have had multiple acute urticaria episodes.
Association between chronic urticaria and thyroid autoimmunity: a prospective study involving 99 patients.
The report assesses Chronic Urticaria Or Hives therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type
Rajouria, "Etiological approach to chronic urticaria," Indian Journal of Dermatology, vol.
8) Verneuil et al demonstrated that the frequency of thyroid autoantibodies was significantly higher in patients with chronic urticaria (26.
So-called silent modes of presentation include bone disease; anemia, including iron-deficiency anemia; weight loss; dermatitis herpetiformis; psoriasis; and chronic urticaria.
Dear AFI: In response to the letter regarding chronic urticaria and angioedeina (AFI November/December 2002), the cause must be identified.

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