heart failure

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heart failure

1. a condition in which the heart is unable to pump an adequate amount of blood to the tissues, usually resulting in breathlessness, swollen ankles, etc.
2. sudden and permanent cessation of the heartbeat, resulting in death

Heart Failure

 

(cardiac insufficiency), a combination of disorders caused primarily by a reduction in cardiac contractility. Heart failure may occur if the heart is overstrained as a result of arterial hypertension or heart disease or if the blood supply to the heart is interrupted (myocardial infarction). Toxic influences, such as those produced during Graves’ disease, and myocarditis may also cause heart failure.

Heart failure is accompanied by congestion, because the weakened cardiac muscle cannot handle circulation. Left ventricular heart failure results in pulmonary congestion accompanied by dyspnea, cyanosis, and hemoptysis, whereas right ventricular heart failure results in passive congestion of systemic circulation marked by the development of edemas and the enlargement of the liver. Heart failure results in hypoxia of the organs and tissues, acidosis, and other metabolic disorders. Acute heart failure usually occurs in the left ventricle and is manifested by an attack of cardiac asthma.

Heart failure is treated with cardiac glycosides, diuretics, and antiarrhythmics. Surgery, for example, the implantation of a pacemaker, may be performed in certain cases.

heart failure

[′härt ‚fāl·yər]
(medicine)
References in periodicals archive ?
Table 34: Chronic Heart Failure Therapeutics Market, Global, Clinical Trials by Phase of Development, 2011 55
In chronic heart failure patients, OXY111A has tremendous potential to improve clinical outcome both in terms of morbidity and mortality and also improved exercise tolerance and therefore quality of life.
It includes a 10-year epidemiological forecast of chronic heart failure prevalence segmented by gender and age (in five-year increments beginning at 45 years and ending at =85 years).
NICE guidelines for the management of chronic heart failure in adults in primary and secondary care.
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About SERVE-HF SERVE-HF is a multinational, multicenter, randomized controlled Phase III study that was designed to assess whether treatment of moderate to severe predominant central sleep apnea with ASV therapy in addition to optimized medical care could reduce mortality and morbidity in patients with symptomatic chronic heart failure.
The SHIFT quality of life study involved 1944 patients with chronic heart failure from 24 countries who were randomised to receive either Procoralan(R) or placebo on top of standard heart failure therapy.
Weight control has become such a strong concept in medicine that many physicians have extended it "in a totally non-evidence-based way" to their patients with chronic heart failure, she observed, adding that her new study provides a clear cautionary message regarding such practice.
The researchers found that the women in the study were more than twice as likely as the men to develop chronic heart failure after the attack.
Synergy is a miniature ventricular support system that offers the potential of a new minimally invasive treatment option for patients with chronic heart failure who are not responding to standard medical care.
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Ferrer"), a leading European pharmaceutical and medical devices company, to commercialize Vasogen's Celacade(TM) technology for the treatment of chronic heart failure in the European Union and in certain Latin American countries.

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