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Inflammation of the pancreas.



acute or chronic inflammation of the pancreas.

Acute pancreatitis may be edematous, hemorrhagic, necrotic, or purulent. It is caused by overeating; by diseases of the stomach, duodenum, biliary tract, or liver; or by stenosis of the gland’s ducts. In acute pancreatitis the pancreas is digested by its own enzymes—trypsin, chymotrypsin, and lipase. When the gland’s tissue decomposes, kinins are released. They decrease arterial pressure and are a factor in blood circulation disorder of both organic and reflex origin in the pancreas. The kinins also cause bile to flow into the gland’s ducts, which damages their walls.

Acute pancreatitis may be marked by very severe abdominal pains, persistent vomiting, and collapse. Complications are peritonitis, abscesses, cysts of the gland, and diabetes mellitus. The disease is treated by narcotics, antibiotics, vasoconstrictors, and such antienzyme preparations as trasilol and contrical and by A. V. Vishnevskii’s paranephric novocain blockade. Serious complications are treated surgically.

In chronic pancreatitis, the gland’s external and internal secretions gradually become insufficient. The disease is treated by diet, antispasmodics, substitutes, cholegogues, antibiotics, and antienzyme preparations. During periods of remission, the patient may receive treatment at a health resort.


Shelagurov, A. A. Bolezni podzheludochnoi zhelezy. Moscow, 1970.


References in periodicals archive ?
There are few studies describing the frequency of pancreatic intraepithelial neoplasia in patients with different pancreatic lesions: pancreatic ductal adenocarcinoma, serous cystadenoma, neuroendocrine tumors, chronic pancreatitis, and other pathologies [16-19].
In further studies of the chronic pancreatitis model, pancreatic lysates obtained from inflamed pancreas were analyzed to characterize the cytokine and chemokine responses accompanying the chronic pancreatic inflammation.
The risk of progression from acute to chronic pancreatitis is higher among alcoholics and smokers, and higher in men than in women.
They estimate that the costs of acute recurrent and chronic pancreatitis in US children are at least $60 to $70 million per year.
However, it causes the disappearance of pancreatic pains in case of CP [11], but without resolution of chronic pancreatitis [2, 13].
chronic pancreatitis, pancreatic cancer, cystic fibrosis, gallstones, cholangitis and biliary atresia are associated with premucosal malabsorption.
Patients with chronic pancreatitis frequently present with pancreatic exocrine insufficiency combined with a persistently low duodenal pH in the postprandial period.
The histologic overlap between PDAC and chronic pancreatitis often further complicates the issue.
Morphological features of chronic pancreatitis on s-MRCP include an irregular, dilated main pancreatic duct and dilated side branches.
The patient continues to suffer intermittent bouts of pancreatitis indicated by elevations of serum lipase levels and has been diagnosed with idiopathic chronic pancreatitis which the patient has learned to live with and control the pain of with over-the-counter analgesics, Nexium, and hydrocodone as needed when pain becomes severe enough.
Exclusion criteria comprised of the age <18yrs, chronic pancreatitis, congenital anomalies of pancreas, pancreatic cancer, cirrhosis and patient with cystic fibrosis.

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