Claisen-Schmidt condensation


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Claisen-Schmidt condensation

[¦klās·ən ¦shmit känd·ən′sā·shən]
(organic chemistry)
A reaction employed for preparation of unsaturated aldehydes and ketones by condensation of aromatic aldehydes with aliphatic aldehydes or ketones in the presence of sodium hydroxide.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Solid Phase Synthesis: Claisen-Schmidt Condensation of 3-Hydroxyacetophenone with Different Substituted Aldehydes and o-Aminothiophenol.
The chalcones were synthesized by using the conventional Claisen-Schmidt condensation method.
The starting [alpha],[beta]-unsaturated carbonyl compound was synthesized by Claisen-Schmidt condensation between 2-hydroxy-3-iodo-5-methylacetophenone and 2-hydroxy4-methyl-5-chlorobenzaldehyde in the presence of solid KOH in combination with grinding at room temperature under solvent-free environment afforded 1-(2'-hydroxy-3'iodo-5'-methylphenyl)-3-(2-hydroxy-4-methyl-5-chlorophenyl)-2-propen-1-one (3).