clathrin

(redirected from Clathrin-coated vesicles)
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clathrin

[′klath·rən]
(cell and molecular biology)
A protein that forms a lattice-shaped coating, through the assembly of subunits called triskelions, on the cytosolic side of membrane regions called coated pits during the initial stages of receptor-mediated endocytosis. Invagination of the pit results in a clathrin-coated vesicle.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The T cell receptor (TCR) stimulation promotes CTLA-4 trafficking from vesicular compartments to the cell membrane, however, once it is already in the membrane, this receptor is continuously endocytosed via clathrin-coated vesicles. After endocytosis, some CTLA-4 molecules are recycled to the cell membrane while others are rapidly degraded in lysosomal compartments (16,17).
Both the constitutive internalization and the internalization of activated PAR1 proceed through clathrin-coated vesicles [13-15].
Nef sequesters the vesicular traffic of the cells through the modulation of some adapter and accessory proteins involved in the formation of clathrin-coated vesicles [55, 56].

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