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Med any sensation or change in bodily function experienced by a patient that is associated with a particular disease



an indication of a phenomenon, for example, of a disease. Many types of symptoms are distinguished in medicine. Constitutional symptoms characterize diseases of varying genesis and include weakness and increases in body temperature. Pathognomonic symptoms indicate a definite nosologic form; a stabbing pain in the epigastric region, for example, is typical of a perforating gastric ulcer. Subjective symptoms are only revealed upon questioning the individual, and objective symptoms are readily observable through examination, palpation, percussion, auscultation, and laboratory and instrumental diagnostic methods. Signal symptoms are the precursors of a disease. They include early symptoms, such as chest pains with pneumonia, and late symptoms, such as peritoneal irritation with cholecystitis.

A disease is said to be atypical if its characteristic symptoms are absent from the very beginning; an example of an atypical disease is the painless form of myocardial infarction. Modern therapeutic measures and protective inoculations can substantially alter the symptoms of a disease and even cause them to disappear. Diagnosis and prognosis are based on a knowledge of all of the symptoms of a disease.


A phenomenon of physical or mental disorder or disturbance which leads to complaints on the part of the patient.
References in periodicals archive ?
Statistical analysis revealed relationship between clinical symptoms and T stage.
In this case, we present a 73-year-old female who, despite having clinical symptoms for a decade, remained undiagnosed until recently.
Although very rare, tumors of the urethrovaginal/vesicovaginal spaces are benign and surgical enucleation after diagnostic imaging (US, MSCT, magnetic resonance imaging) is final treatment with good prognosis and absence of clinical symptoms of dyspareunia, chronic pelvic pain, dysuria and incontinence.
Treatment was determined as effective if some clinical symptoms still remained but relieved compared to before treatment and mucosal lesions reduced for more than 50% under gastroscope.
These neural changes take time to reach the subjective conscious mind, which is why improvement in clinical symptoms of depression doesn't manifest until 2-3 weeks into therapy, with the drug's full effects not seen until 6-7 weeks (Br J Psychiatry.
Mesoblast Chief Executive Silviu Itescu said in the statement: "The Phase 2 trial results have indicated a strong efficacy signal and consistent effects of a single MPC infusion on clinical symptoms, functional abilities, and disease activity, without any serious adverse events."
[4] Clinical symptoms observed in babies born to pregnant women using anticholinesterase agent may be insignificant within first 24 h, but it will not take longer than 72 h for the clinical table to settle down.
The trial was designed to confirm the safety and demonstrate the anti-inflammatory effect of Cx611 on the sepsis-like clinical symptoms and immunological response elicited by an intravenous administration of a bacterial endotoxin (lipopolysaccharide) in healthy volunteers.
High frequency of persistent viral infections with various representatives of the microflora, uncertain clinical symptoms and asymptomatic course for a long time were the main reasons for inadequate attitude to these diseases [7, 8, 9, 10].
The main clinical symptoms of cystitis glandularis accompanied with upper urinary tract obstruction were renal or abdominal pain; a few patients had nausea, vomiting, bladder irritation, hematuria and fever.
However, as modern medicine hones new techniques--primarily brain imaging and biomarker testing--to identify people who do not yet have clinical symptoms but are at risk for Alzheimer's, the focus in clinical trials is shifting from people with dementia to people with no symptoms but who do have imaging and biofluid signs of pathology
Solitary extramedullary plasmacytoma is a rare hematologic malignancy with nonspecific clinical symptoms and imaging findings.

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