Also found in: Dictionary, Medical, Wikipedia.
Related to Clonorchiasis: schistosomiasis, opisthorchiasis


A parasitic infection of humans and other fish-eating mammals which is caused by the trematode Opisthorchis (Clonorchis) sinensis, which is usually found in the bile ducts.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a helminthic disease of man, cats, dogs, and certain other mammals caused by the flatworm Clonorchis sinensis, which infests the bile ducts, gallbladder, and pancreatic ducts.

Chlonorchiasis is widespread in China, Japan, Korea, and, in the USSR, the Far East. The source of infection is an individual affected with the parasite; animals are of secondary importance as a source. The eggs of the flukes, excreted with the feces and reaching a body of water, are taken up by mollusks (Bithynia bongicornis and others). The helminth develops within the mollusk until it reaches the cercaria stage. The cercaria emerge and penetrate carp (and, possibly, certain crustaceans), within which they change into metacercaria. Human beings and animals become infected when they eat raw, inadequately cooked, or inadequately salted fish. A fever develops two to four weeks after a person becomes infected, the number of eosinophils in the blood increases, and the liver (and sometimes the spleen) become enlarged. Several weeks later these symptoms subside and the disease becomes chronic with brief, intermittent exacerbations. Clonorchiasis causes functional disturbances (dyskinesia) of the biliary tract, hepatitis, pancreatitis, and, sometimes, cirrhosis of the liver. Diagnosis is based on the detection of the fluke eggs in the feces or duodenal contents. A specific agent, chloxylum, as well as cholagogic and antispasmodic agents, are used in treatment, and the biliary tract should be drained. Chlonorchiasis can be prevented by keeping lakes and streams free of pollution by feces and by cooking fish properly (boiling, thorough frying, hot smoking, pickling for two or three weeks).

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
Mentioned in ?
References in periodicals archive ?
Pulmonary involvement is common in paragonimiasis but rare in clonorchiasis. Clonorchiasis complicated with pulmonary involvement has been reported in Germany, Korea, and China.[3],[4],[5] However, only a few parasites cause diffuse parenchymal lung disease (DPLD).
Clonorchiasis complicated with diffuse parenchymal lung disease in children.
Wei, "Overview of human clonorchiasis sinensis in China," Southeast Asian Journal of Tropical Medicine and Public Health, vol.
Fang, "Clonorchis sinensis and clonorchiasis, an update," Parasitology International, vol.
Clonorchiasis Worms reproduce in gastropod snails, then are swallowed by freshwater fish or other snails.
Source: WHO 1996 (205) except amoebic dysentery, bacillary dysentery dracunculiasis, dengue and RVF from WHO 1998 (200); and clonorchiasis and paragonimiasis from Muller & Morera 1994 (119).
Our team has just evaluated the diagnosis performance of four immunological diagnosis kits for clonorchiasis in China.[5] It is found that among the many different heterologous sera from cases with other parasitic diseases (including schistosomiasis, paragonimiasis, trichinellosis, ascariasis, hookworm disease, and trichuriasis), those from paragonimiasis show most serious cross-reactivity to the antigens of C.
in the reference is used for diagnosis of sparganosis mansoniother than clonorchiasis.[6] Wang et al .
We used data from surveys 1-3 to determine epidemiologic changes in STHs and clonorchiasis over time in Hengxian County.
The symptoms of clonorchiasis are indigestion, abdominal discomfort, and diarrhea; it may also be asymptomatic.
For example, in 1995, an estimated 19 million people (44%) in the Republic of Korea were at risk for clonorchiasis. Applying the latest United Nations national population statistics (19), we estimate that 21 million people are now at risk for infection with C.
The growing volume of international travel and population migration, facilitated by increasing availability of air transportation, is responsible for cases of opisthorchiasis and clonorchiasis diagnosed in non-disease-endemic countries, mainly in North America.