clotting factor

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clotting factor

[′kläd·iŋ ‚fak·tər]
(physiology)
Any of several plasma components that are involved in the clotting of blood, such as fibrinogen, prothrombin, and thromboplastin.
References in periodicals archive ?
They are classified according to which clotting factor is deficient.
Genetic aberrations with impaired synthesis or functional defects are responsible for hereditary forms of reduced clotting factor activity, as seen in hemophilias A (factor VIII), B (factor IX), and C (factor XI).
From these retrospective data, it appears evident that the severely injured, coagulopathic patient needs not only oxygen carrying capacity and volume from packed red blood cells, but also clotting factors from FFP in a high ratio approaching a 1:1 ratio.
Some civilian surgical teams have also recommended increasing the focus on early and aggressive replacement of clotting factors in the resuscitation process following massive hemorrhage.
In a series of eight consecutive hemophiliac patients with chronic hepatitis C virus (HCV) infection treated at one center with a combination of ribavirin and interferon alfa-2b, five patients had moderate or severe hemophilia that required significantly less use of clotting factors on average during each month of treatment than in the 6 months prior to combination therapy (1,605 U/mo vs.
Such women are known to have reduced levels of clotting factors, usually about 50% below normal, regardless of the severity of the hemophilia they carry (Lancet 362[9381]:351-54, 2003).
They did, however, seek to simplify their analysis by stripping the plasma of clotting factors.
Predicting risks associated with these transient alterations in inflammatory and clotting factors will require more research and discussion.
One British adult dies from the disease every three minutes and high levels of clotting factors in blood are a major risk element.
People with hemophilia inject themselves with the clotting factors on average three times per month unless they are on a preventive regimen, in which case they could do it several times a week.
Cryoprecipitate is the product made from clotting factors separated from frozen plasma.
Those who plan to travel in countries where Hepatitis A is prevalent, live in an area where it is common, receive clotting factors, or engage in high risk behaviors should receive the Hepatitis A vaccine.