56 SGLT2 belongs to the family of sodium glucose co-transporters.
Therefore these co-transporters are an example of secondary active transport.
Quantification of mRNA levels of the Na-Pi co-transporters showed a significant increase of NaPi-IIb mRNA levels in the ileum of chickens fed the 0.
To determine the effects of dietary Pi on the expression of the chicken intestinal Na-Pi co-transporter, experimental diets were formulated to be deficient in total Pi.
It appears that a major function of circulating FGF23 is the control of the expression of the renal tubular sodium dependent phosphate co-transporters
(NaPi 2a and 2c) and thus renal tubular phosphate reabsorption.
Type II co-transporters
facilitate the majority of tubular phosphate reabsorption and are the main target for regulating phosphate by PTH and dietary phosphate content.
1) Reduction of Energy Uptake from the GI and Genitourinary Tract 1a) Inhibitors of Panreatic Lipase 1b) Inhibitors of Intestinal Microsomal Trigliceride Transfer Protein (MTP) 1c) Inhibitors of Acyl-CoA:diacyl-glycerol acyltransfe-rase 1 (DGAT1) 1d) Inhibitors of Low-Affinity Sodium-Dependent Glucose Co-transporters
(SGLT2) 1e) Others
Regulation of intestinal Na+-dependent phosphate co-transporters
by a low-phosphate diet and 1,25-dihydroxyvitamin [D.