Stanley Cohen

(redirected from Cohen, Stanley)
Also found in: Medical.

Cohen, Stanley,

1922–2020, American biochemist, b. New York City, Ph.D. Univ. of Michigan, 1948. Cohen did his most important work at Washington Univ. with Rita Levi-MontalciniLevi-Montalcini, Rita
, 1909–2012, Italian-American neurologist, b. Turin, Italy, M.D. Univ. of Turin, 1936. A dual citizen of Italy and the United States, Levi-Montalcini did her most important work with Stanley Cohen at Washington Univ.
..... Click the link for more information.
 in the 1950s. Studying mouse tumors implanted in chicken embryos, she discovered nerve growth factor, which he subsequently isolated. He also discovered and isolated epidermal growth factor and its receptor. These were the first of many cell growth factors found in animals. The discovery of nerve growth factor radically changed the study of cell growth and development, and the discovery of epidermal growth factor and its receptor eventually led to new approaches to the treatment of cancer. For this discovery Levi-Montalcini and Cohen were awarded the 1986 Nobel Prize in Physiology or Medicine. In 1959 Cohen moved to Vanderbilt Univ., where he became a professor, retiring in 1999.
The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved.

Cohen, Stanley

(1922–  ) cell biologist; born in New York City. He taught at the Universities of Michigan (1946–48) and Colorado (1948–52) before joining Rita Levi-Montalcini's laboratory at Washington University (St. Louis, Mo.) (1953–59). He discovered the epidermal growth factor from mouse tissue extract, which accelerated the maturation of newborn mice. He continued his studies of this substance at Vanderbilt University (1959–86), determining its amino acid sequence and action on cells and wound healing. In 1986, he and Levi-Montalcini received the Nobel Prize in physiology for their fundamental contributions to cell and organ development.
The Cambridge Dictionary of American Biography, by John S. Bowman. Copyright © Cambridge University Press 1995. Reproduced with permission.