Julius Friedrich Cohnheim

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Cohnheim, Julius Friedrich


Born July 20, 1839, in Demmin, Pomerania; died Aug. 15, 1884, in Leipzig. German pathologist.

Cohnheim studied medicine at the universities of Würzburg, Marburg, Greifswald, and Berlin. In 1864 he was an assistant to R. Virchow. Cohnheim was professor of pathological anatomy at Kiel from 1868, Breslau (now Wroclaw) from 1872, and Leipzig from 1878 to 1884. His principal work was a manual in general pathology, in which he set forth a theory of the origin of tumors (”Cohnheim’s embryonic theory”). According to this theory, tumors are formed from embryonic rudiments that remain unutilized during the origin and growth of the embryo; subsequently, when the life processes of surrounding tissues slacken, these cells, in Cohnheim’s opinion, begin to reproduce intensively. He eleborated a vascular theory of inflammation and a theory concerning the terminal arteries (vessels) and the pathogenesis of an infarct. Cohnheim’s works greatly influenced the development of pathology.


Obshchaia patologiia, vols. 1–2. St. Petersburg, 1878–81.
Bugorchatka s tochki zreniia infektsionnoi teorii. St. Petersburg, 1880.


Serov, V. “Iulius Fridrikh Kongeim (K 75-letiiu so dnia smerti).” Arkhiv patologii, 1959, vol. 21, no. 9.
References in periodicals archive ?
After defending his doctoral dissertation in 1886 under the direction of Julius Cohnheim, MD, Hansemann worked as an assistant to Rudolf Virchow, MD, and then held in succession the positions of lecturer, nominal professor, and honorary professor of pathologic anatomy at the University of Berlin.
In 1868 using the technique taught to him by Julius Cohnheim, 1839-1884), he stained a sample of human skin with gold chloride and described the dendritic cells in the skin which now bear his name and which from their morphology he believed to be nerve cells.
The relationship between cancer and embryonic tissues was first proposed in the 1870s by Francesco Durante and Julius Cohnheim, who thought that cancers originated from cells in adults that persist in an immature, embryonic-like state.
Briefly speaking, the idea of mesenchymal stem cells was initially introduced by Cohnheim as a nonhematopoietic and mesoderm-derived population in the bone marrow [33].