cold agglutinin

(redirected from Cold agglutinin disease)
Also found in: Dictionary, Thesaurus, Medical, Wikipedia.
Related to Cold agglutinin disease: cold antibody

cold agglutinin

[′kōld ə′glüt·ən·ən]
(immunology)
A nonspecific panagglutinin found in many normal human serums which produce maximum clumping of erythrocytes at 4°C and none at 37°C.
References in periodicals archive ?
TNT009 is currently in clinical development for the treatment of Cold Agglutinin Disease (CAD), a rare disease in hematology.
Thrombocytopenia and even pancytopenia may be present, as well as a cold agglutinin disease characterized by an autoimmune hemolytic anemia.
Clues to the diagnosis of cold agglutinin disease include acrocyanosis and Raynaud's phenomenon.