collagenase

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collagenase

[′kä·lə·jə‚nās]
(biochemistry)
Any proteinase that decomposes collagen and gelatin.
References in periodicals archive ?
Finally, boron has an impact in the consistency of the hepatic connective tissue since collagen deposits are diminished after exposure to the metalloid, shifting part of collagen type I to collagen type III, a finding that in other tissues has been reported to imply collagenolysis and a consequent weakening of the supporting role of collagen architecture.
Evidence for increased collagenolysis by interstitial collagenases-1 and-3 in vulnerable human atheromatous plaques.
Inhibition by Retinoic Acid of Type IV Collagenolysis and Invasion Though Reconstituted Basement Membrane by Metastatic Rat Mammary Adenocarcinoma Cells Cancer Research 49 (7): 1698-1706.
Variable diameter of collagen fibrils found in this region and their breakdown into a granular deposit are typical for collagenolysis, as, for example, in the human uterine cervix when giving birth (Junqueira et al.
Keratomalacia is commonly encountered in dogs where there is rapid breakdown of corneal epithelium leading to melting of stroma or collagenolysis.
Collagenase activity in the conditioned media from skin and pubocervical fascia biopsy explant cultures is higher in biopsies taken from women with SUI; that circulating collagenolytic activity is higher in women with SUI and that urinary levels of collagen degradation products are higher in women with SUI, all provide supportive evidence for increased collagenolysis in the aetiology of SUI.