competitive inhibition

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competitive inhibition

[kəm′ped·əd·iv ‚in·ə′bish·ən]
(biochemistry)
Enzyme inhibition in which the inhibitor competes with the natural substrate for the active site of the enzyme; may be overcome by increasing substrate concentration.
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In both major types of PTP1B inhibitors, the competitive inhibitors of higher activities (Table 1) and selectivity were chosen for analysis.
Hirsutism stemming from hyperandrogenism often can be lessened by competitive inhibitors of the androgen receptor.
Khan and Atta-Ur-Rahman, Kinetics of Novel Competitive Inhibitors of Urease Enzymes by a Focused Library of Oxadiazoles / Thiadiazoles and Triazoles, Biochem.
"The new dimerization inhibitor unveils a biologically meaningful rationale for suppressing angiogenesis in tumors that could outperform traditional competitive inhibitors of angiogenesis in tumor therapy.
Hirsutism that is associated with hyperandrogenism often can be lessened by drugs that are competitive inhibitors of the androgen receptor.
Considering the findings to date, it is reasonable to postulate the hemodialysis-induced cascade interaction model in fatty acid-uremic toxin-drug systems, in which a transient increase in the concentrations of long-chain fatty acids could produce a cascade displacement of both site I- and II-bound drugs by their competitive inhibitors, namely, CMPF and uremic toxins that contain an indole ring (see Fig.

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