Coniine


Also found in: Dictionary, Wikipedia.

coniine

[′kō·nē·ən]
(pharmacology)
C5H10NC3H7 A colorless, oily liquid with a mousy odor and a boiling point of 166°C; soluble in alcohol, ether, and oils; used as a sedative. Also known as propylpiperidine.

Coniine

 

C8H17N a basic alkaloid and toxic agent of poison hemlock. A colorless liquid with a pungent odor, it dissolves readily in organic solvents; it is slightly soluble in water. Coniine occurs in all parts of plants, primarily in the fruits and seeds (up to 1 percent). It is formed in plant cells from acetic acid and lysine amino-acid radicals. The German chemist A. Ladenburg first synthesized the natural alkaloid in 1886. Coniine is a strong poison with a neuroparalytic effect.

References in periodicals archive ?
into coniine. With that in mind, Leete came to the conclusion that
acetate played the role of the carbon backbone for coniine, rather than
In later experiments, it was observed that when coniine
concentrations of coniine were associated with higher concentrations of
a precursor role in the biosynthetic mechanism of coniine.
The conversion of coniine into [gamma]-coniceine and vice versa was
reduced to coniine through the action of an [gamma]-coniceine reductase.
The interconversion of [gamma]-coniceine into coniine and the
Isolation of insect paralyzing agent coniine from Sarracenia Jlava.
(99) The most important are coniine that causes initial stimulation followed by depression of the nervous system and [gamma]-coniceine (effects similar to those of nicotine).
(PIM 144) 8, http://www.inchem.org/documents/pims/ plant/conium.htm: Three mg of coniine are said to produce symptoms in an adult, 150 mg have been tolerated; 30-60 mg may be considered dangerous, death has been caused by doses greater than 100 mg.
(100) 'Coniine', http://www.chm.bris.ac.uk/webprojects2001/gerrard/coniine.html.