consensus sequence


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consensus sequence

[kən′sen·səs ‚sē·kwəns]
(genetics)
An average nucleotide sequence; each nucleotide is the most frequent at its position in the sequence.
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Recently it was confirmed that consensus sequences forming stable G-quadruplex structures are responsible for RNA replication and inhibition of protein translation of hepatitis C virus [14].
Partial sequences from the NCBI DNA sequence database that match segments of the consensus sequence shown in Fig.
Briefly, consensus sequences from the WSB, PWK, and CAST strains were mapped to the alignment and gaps filled with Ns.
Two individuals were found to have an identical consensus sequence for the genotyped C*14:02:01 allele, which harbors 2 distinct polymorphisms, resulting in the reporting of only a single novel allele sequence.
RT-PCR was performed to confirm our speculation about the FAMLF consensus sequence. Two peripheral blood samples from AL patients were amplified by RT-PCR and a specific band of expected size (2214 bp) was obtained, as well as an unexpected 429-bp band (Figure 1).
The final population of sequences studied was the following: 15 consensus sequences for the histidine kinases, REC/25 consensus sequences, and HTH_AraC/15 consensus sequences for response regulators.
The higher the depth of read coverage, the better statistical strength this consensus sequence has, as correct reads at any individual position increasingly outnumber individual read errors.
In Escherichia coli the SOS gene network is under control of the RecA protein which, as consequence of DNA damage, induces the autoproteolysis of LexA repressor which binds the 16 bp palindromic consensus sequence named LexA-binding box.
The major difference is that it begins with a consensus sequence containing degenerate bases and selects primers with fewer than 3 or 4 degenerate bases, so that in the end a majority of strains are amplified, but it does not require primers to amplify all strains.
This T-cell epitope is observed in all the serological variants of DEN, with each serotype having its distinct consensus sequence for the epitope.