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(hī'drəkôr`tĭzōn'), another name for the steroid hormone cortisolcortisol
or hydrocortisone,
steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland. Like cortisone, cortisol is classed as a glucocorticoid; it stimulates liver glycogen formation while it decreases the rate
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, more especially used to refer to preparations of this hormone used medicinally. Hydrocortisone, introduced in 1952, is more potent than cortisonecortisone
, steroid hormone whose main physiological effect is on carbohydrate metabolism. It is synthesized from cholesterol in the outer layer, or cortex, of the adrenal gland under the stimulation of adrenocorticotropic hormone (ACTH).
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 with respect to medicinal metabolic and anti-inflammatory effects. Like cortisone, it is used to treat Addison's diseaseAddison's disease
[for Thomas Addison], progressive disease brought about by atrophy of the outer layer, or cortex, of the adrenal gland; it is also called chronic adrenocortical insufficiency.
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, inflammatory and rheumatoid diseases, and allergies. Low-potency hydrocortisone, available over the counter, is used to treat skin irritations. See also corticosteroid drugcorticosteroid drug
, any one of several synthetic or naturally occurring substances with the general chemical structure of steroids. They are used therapeutically to mimic or augment the effects of the naturally occurring corticosteroids, which are produced in the cortex of the
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; steroidssteroids,
class of lipids having a particular molecular ring structure called the cyclopentanoperhydro-phenanthrene ring system. Steroids differ from one another in the structure of various side chains and additional rings. Steroids are common in both plants and animals.
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The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



(17-hydroxycorticosterone, cortisol), one of the glucocorticoids; a hormone formed in the adrenal cortex and predominantly regulating carbohydrate metabolism. The human adrenal glands secrete from 5 to 30 mg of hydrocortisone per day, although formation of hydrocortisone may increase five times under conditions of stress or upon introduction of adrenocorticotropic hormone.

Hydrocortisone is used in medical practice as a hormonal preparation that exerts an anti-inflammatory and antiallergic effect. Hydrocortisone (and hydrocortisone acetate in the form of a suspension) is prescribed for the treatment of rheumatism, bronchial asthma, leukemia, and endocrine and other diseases; it is used locally (most often in the form of a cream) for eczema, neurodermatitis, and eye diseases.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


C21H30O5 The generic name for 17-hydroxycorticosterone; an adrenocortical steroid occurring naturally and prepared synthetically; its effects are similar to cortisone, but it is more active. Also known as cortisol.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The Cortaid Poison Ivy Treatment Spray is designed to relieve the pain and itching as well as help heal any rash.
Cortaid's Advanced 12 Hour Anti-Itch cream is the longest lasting maximum strength hydrocortisone cream available without a prescription.
In addition to strong international sales for Neutrogena, J&J credited the strong growth in skin care sales last year to a good performance by Aveeno and the acquisitions of Balmex and Cortaid. The company maintains that its biggest opportunity for growth in skin care is to broaden the geographic presence of its current brands and continuously provide new skin care therapies to people of all ages around the world.
J&J is behind such familiar first aid products as Band-Aid bandages, Caladryl anti-itch lotion, Neosporin antibiotic ointment and Cortaid anti-itch cream.
(+3.9%) Dollar Dollar LEADING Market sales sales BRANDS ** share (000) % change Cortizone 10 7.9% $16,044 + 19.5% Benadryl 7.9% 15,960 + 4.1% Sarna 4.9% 9,899 + 6.1% Aveeno 4.9% 9,842 - 12.5% Cortaid 4.4% 8,859 - 19.7% Cortizone 10 Plus 3.8% 7,590 + 7.2% Lotrimin AF 3.2% 6,494 + 5.7% Zanfel 2.4% 4,774 - 6.7% Lotrimin Ultra 2.0% 4,066 + 2.3% Gold Bond 2.0% 3.94 - 7.6% TOTAL UNIT SALES* 53.9 mil.
Best first aid product: Cortaid Poison Ivy Care Treatment Kit
For example, Johnson & Johnson's Cortaid Poison Ivy Care Treatment Kit includes a Removal Scrub that binds to urushiol, washing it away.