Some immunosuppresive agents such as calcinerin inhibitors and corticosteriods
have dose-related effects on serum lipid levels.
Each corticosteroid is metabolized differently and each has a different potency.
Asthma patients who are treated with 40 to 60 mg per day of oral corticosteriods
for long periods of time are most likely to experience bone loss.
Infants with a known or suspected immunodeficiency disease or infants in whom the immune status is compromised, as in patients who are receiving chemotherapy, radiation treatments, or long term treatment with systemic corticosteriods
, should not receive the vaccine.
Occasionally even anti-inflammatory medications such as corticosteriods
may be necessary to promote healing.
Still another group of youngsters who may be at increased risk are those taking long-term or high-dose corticosteriods
for such chronic conditions as asthma or arthritis.
Improving preterm survival by antenatal corticosteriods
, early resuscitation care and improving preterm transport.
It may interact with anti-inflammatory drugs (paracetamol, ibuprofen), corticosteriods
, beta-blockers, anti-psychotics, anti-coagulates and drugs to control epilepsy.
Previous use of inhaled or oral corticosteriods
Other conditions that contribute to a weak, compromised immune system are substance abuse, diabetes mellitus, silicosis, cancer of the head or neck leukemia or Hodgkin's disease, chronic renal failure, low body weight, and certain medical treatments such as corticosteriods