corticotropin-releasing hormone

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corticotropin-releasing hormone

[‚kȯrd·ə·kō′trō·pən ri¦lēs·iŋ ‚hȯr‚mōn]
(biochemistry)
A substance produced by the hypothalamus that stimulates the pituitary gland to produce adrenocorticotropic hormone (ACTH). Abbreviated CRH.
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References in periodicals archive ?
Theoharides, "Acute immobilization stress triggers skin mast cell degranulation via corticotropin releasing hormone, neurotensin, and substance P: a link to neurogenic skin disorders," Brain, Behavior, and Immunity, vol.
Tsukamoto et al., "Effect of prolonged exposure to low concentrations of formaldehyde on the corticotropin releasing hormone neurons in the hypothalamus and adrenocorticotropic hormone cells in the pituitary gland in female mice," Brain Research, vol.
Hypothalamic-pituitary-adrenal axis functioning and cerebrospinal fluid corticotropin releasing hormone and corticotropin levels in alcoholics after recent and long-term abstinence.
Corticotropin releasing hormone expression is the major target for glucocorticoid feedback-control at the hypothalamic level.
Corticotropin releasing hormone: relevance to normal physiology and to the pathophysiology and differential diagnosis of hypercortisolism and adrenal insufficiency 1987; 43:183-200.
The secretion of the corticotropin releasing hormone (CRH) reflects this activity of the HPA axis and CRH "instructs" the body to slow the activity in certain areas and thus balances the reaction of the body to stress.

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