corticotropin-releasing hormone

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corticotropin-releasing hormone

[‚kȯrd·ə·kō′trō·pən ri¦lēs·iŋ ‚hȯr‚mōn]
(biochemistry)
A substance produced by the hypothalamus that stimulates the pituitary gland to produce adrenocorticotropic hormone (ACTH). Abbreviated CRH.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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Amygdala-mediated mechanisms regulate visceral hypersensitivity in adult females following early life stress: Importance of the glucocorticoid receptor and corticotropin-releasing factor. Pain.
Aston-Jones, "Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus," Brain Research, vol.
Young III, "Lactation inhibits stress-mediated secretion of corticosterone and oxytocin and hypothalamic accumulation of corticotropin-releasing factor and enkephalin messenger ribonucleic acids," Endocrinology, vol.
Cellular signaling protective against noise-induced hearing loss-A role for novel intrinsic cochlear signaling involving corticotropin-releasing factor? Biochem Pharmacol 2015; 97: 1-15.
[21.] Familari M, Smith AI, Smith R, Funder JW Arginine vasopressin is a much more potent stimulus to ACTH release from ovine anterior pituitary cells than ovine corticotropin-releasing factor. 1.
Koob, "Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal," Brain Research, vol.
Corticotropin-releasing factor 2 receptor (CRF2R) is suggested to play a fundamental role in the recovery from stress to calm (Bale et al., 2002).
Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF)family with high affinity for the CRF2 receptor.
Corticotropin-releasing factor in the basolateral amygdala enhances memory consolidation via an interaction with the beta-adrenoceptor-cAMP pathway: dependence on glucocorticoid receptor activation.
Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?
(1988) Acetylcholine and norepinephrine stimulate the release of corticotropin-releasing factor from the rat hypothalamus in vitro.
Furthermore, the serotonergic, noradrenergic, corticotropin-releasing factor and cannabinoid systems seem to play an important role in the neurobiology of alcoholism.

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