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Related to Coxsackie virus: herpangina, echovirus


A large subgroup of the genus Enterovirus in the family Picornaviridae. The coxsackieviruses produce various human illnesses, including aseptic meningitis, herpangina, pleurodynia, and encephalomyocarditis of newborn infants. See Picornaviridae

Coxsackieviruses measure about 28 nanometers in diameter; they resemble other enteroviruses in many biological properties, but differ in their high pathogenicity for newborn mice. At least 23 antigenically distinct types in group A are now recognized, and 6 in group B.

After incubation for 2–9 days, during which the virus multiplies in the enteric tract, clinical manifestations appear which vary widely. Diagnosis is by isolation of virus in tissue culture or infant mice. Stools are the richest source of virus. Neutralizing and complement-fixing antibodies form during convalescence and are also useful in diagnosis. See Antibody, Complement-fixation test

The coxsackieviruses have worldwide distribution. Infections occur chiefly during summer and early fall, often in epidemic proportions. Spread of virus, like that of other enteroviruses, is associated with family contact and contacts among young children. See Animal virus, Virus classification


A large subgroup of the enteroviruses in the picornavirus group including various human pathogens.
References in periodicals archive ?
To study the serological prevalence of Coxsackie virus in acute pericarditis and myocarditis in a Tertiary Centre.
Dwyer also notes that a particular Coxsackie virus (a denizen of the intestinal tract) can trigger off immunological attacks.
DISCUSSION: Hand-Foot-Mouth disease is an acute highly contagious disease caused by several enteroviruses, such as coxsackie virus A6, A10, A16 and enterovirus 71.
The most common cause of the disorder is a viral infection, usually with the coxsackie virus.
This is really just the tip of the iceberg, because if you do not have Candida or cytomegalovirus (CMV) or Coxsackie virus or chlamydia or Lyme disease, odds are that you will acquire something else such as a parasite.
dagger]) The following viruses were tested for herpes simplex virus (HSV) type 1, HSV-2, varicella-zoster virus (HSV-3), Epsetin-Barr virus (human herpesvirus [HHV] type 4), cytomegalovirus (HHV-5), (HHV-6), HHV-7, HHV-8, dengue virus, Japanese encephalitis virus, rubella virus, West Nile virus, yellow fever virus, tick-borne encephalitis virus, Nipah virus, measles virus, mumps virus, parainfluenza virus, respiratory syncytial virus, metapneumovirus, Chikungunya virus, Sindbis virus, Semliki Forest virus, eastern equine encephalitis virus, western equine encephalitis virus, poliovirus, Coxsackie virus, echovirus, enterovirus, lyssaviruses, and Chandipura virus.
The result of throat culture was normal so nasopharyngeal swab was taken for microscopic inspection and tularemia, Coxsackie virus A-B and adenovirus IgM and IgG antibodies and diphtheria toxin were prospected.
Conjunctivitis epidemics in Dar es Salaam have been due to enteroviruses 70 (EV-70), coxsackie virus A24, adenoviruses and gonococcal ophthalmia, (4) which cause photophobia, watering, foreign body sensation, eyelid oedema, conjunctival haemorrhages and superficial punctuate keratitis (acute haemorrhagic conjunctivitis).
Determination of virus-induced cytopathogenic effects and virus titres revealed that EPs [R] 7630 at concentrations up to 100 [micro]g/ml interfered with replication of seasonal influenza A virus strains (H1N1, H3N2), respiratory syncytial virus, human coronavirus, parainfluenza virus, and coxsackie virus but did not affect replication of highly pathogenic avian influenza A virus (H5N1), adenovirus, or rhinovirus.
In 1987, she was diagnosed with cardiomyopathy caused by a Coxsackie virus infection.
40, 41 Dilated cardiomyopathy Coxsackie virus, other 42 enteroviruses Chronic Neurological diseases Multiple sclerosis Various infectious 43-45 agents ?