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Related to Coxsackie virus: herpangina, echovirus


A large subgroup of the genus Enterovirus in the family Picornaviridae. The coxsackieviruses produce various human illnesses, including aseptic meningitis, herpangina, pleurodynia, and encephalomyocarditis of newborn infants. See Picornaviridae

Coxsackieviruses measure about 28 nanometers in diameter; they resemble other enteroviruses in many biological properties, but differ in their high pathogenicity for newborn mice. At least 23 antigenically distinct types in group A are now recognized, and 6 in group B.

After incubation for 2–9 days, during which the virus multiplies in the enteric tract, clinical manifestations appear which vary widely. Diagnosis is by isolation of virus in tissue culture or infant mice. Stools are the richest source of virus. Neutralizing and complement-fixing antibodies form during convalescence and are also useful in diagnosis. See Antibody, Complement-fixation test

The coxsackieviruses have worldwide distribution. Infections occur chiefly during summer and early fall, often in epidemic proportions. Spread of virus, like that of other enteroviruses, is associated with family contact and contacts among young children. See Animal virus, Virus classification


A large subgroup of the enteroviruses in the picornavirus group including various human pathogens.
References in periodicals archive ?
We are indebted to Margery Kennett for the generous gifts of human enterovirus 71 and coxsackie virus A antisera.
The most common cause of the disorder is a viral infection, usually with the coxsackie virus.
Meanwhile, the number of chronic viruses to consider continued to expand, including herpesvirus 6 (HHV-6), cytomegalovirus (CMV), Coxsackie virus, parvovirus B19, echovirus, and hepatitis (HCV)--to name a few.
The result of throat culture was normal so nasopharyngeal swab was taken for microscopic inspection and tularemia, Coxsackie virus A-B and adenovirus IgM and IgG antibodies and diphtheria toxin were prospected.
Conjunctivitis epidemics in Dar es Salaam have been due to enteroviruses 70 (EV-70), coxsackie virus A24, adenoviruses and gonococcal ophthalmia, (4) which cause photophobia, watering, foreign body sensation, eyelid oedema, conjunctival haemorrhages and superficial punctuate keratitis (acute haemorrhagic conjunctivitis).
An outbreak of acute hemorrhagic conjuctivits caused by Coxsackie virus A24 variant in Pakistan.
Determination of virus-induced cytopathogenic effects and virus titres revealed that EPs [R] 7630 at concentrations up to 100 [micro]g/ml interfered with replication of seasonal influenza A virus strains (H1N1, H3N2), respiratory syncytial virus, human coronavirus, parainfluenza virus, and coxsackie virus but did not affect replication of highly pathogenic avian influenza A virus (H5N1), adenovirus, or rhinovirus.
In 1987, she was diagnosed with cardiomyopathy caused by a Coxsackie virus infection.
Studies for serologic markers of viral hepatitis revealed no acute or chronic infection with cytomegalovirus, Epstein-Barr virus, herpes simplex virus, coxsackie virus, or hepatitis A, B, or C viruses.
40, 41 Dilated cardiomyopathy Coxsackie virus, other 42 enteroviruses Chronic Neurological diseases Multiple sclerosis Various infectious 43-45 agents ?
Q I AM a 25-year-old male and have coxsackie virus.