Crimean-Congo hemorrhagic fever

(redirected from Crimean-Congo haemorrhagic fever)
Also found in: Medical.

Crimean-Congo hemorrhagic fever,

acute, sometimes fatal disease endemic in many parts of Eurasia and Africa, caused by a tick-borne virus. The virus, an RNA virus (Nairovirus) of the Bunyaviridae family, is typically transmitted to humans by ticks of the genus Hyalomma, although humans are not their preferred hosts. It usually incubates for one to six days (though it can be up to 13 days) before an infected person suddenly develops such symptoms as high fever, headache, neck, back, muscle, joint, or abdominal pain, dizziness, vomiting and diarrhea, sensitivity to light, petechiae (red spots caused by bleeding in the skin) in mouth and throat, jaundice, and in severe cases mood changes and confusion sometimes followed by exhaustion and sleepiness. After several days, large areas of bleeding under the skin resembling bruises as well as uncontrolled nosebleeds and other bleeding may develop; in severe cases kidney deterioration or liver or pulmonary failure may follow. There is no cure or vaccine for the disease; patient treatment involves managing the symptoms and treating any secondary infection. The antiviral drug ribavirin may provide some benefit, but its efficacy has not been confirmed. Death occurs in 10% to 40% of the cases; survivors recover slowly.

The virus is most commonly contracted by herders and other agricultural workers from adult ticks on infected domestic livestock; the virus, however, generally does not cause disease in livestock and other animals, such as hares, hedgehogs, and other small wild mammals that host the immature ticks. Infections also commonly occur among slaughterhouse workers and among medical personnel and others who are in close contact with the blood and other bodily fluids of an infected individual.

The disease was first identified in Crimea in 1944 and called Crimean hemorrhagic fever. In the 1950s and 60s a virus was isolated in the Belgian Congo and subsequently described; the then-named Congo virus was later determined to be identical to a virus isolated (1967) from a Central Asian patient with Crimean hemorrhagic fever. The disease was given its current official name in 1973.

The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/
Mentioned in ?
References in periodicals archive ?
KARACHI -- One more Crimean-Congo Haemorrhagic Fever (CCHF) case surfaced in Karachi on Wednesday, taking the number of reported cases to 31 since the 1st January 2019.
KARACHI -- Crimean-Congo haemorrhagic fever (CCHF) has claimed the life of a septuagenarian man at a private hospital in Karachi, taking the total death toll caused by the deadly infection to 10 reported so far this year in the city, officials said on Saturday.
KARACHI -- The Crimean-Congo Haemorrhagic Fever (CCHF) has claimed two more lives in Karachi and death toll from the tick-born viral disease has climbed to nine in the megacity this year.
RAWALPINDI -- The District Health Authority (DHA) has started training livestock department staff to check animals for fleas known to cause Crimean-Congo haemorrhagic fever (CCHF) commonly known as Congo fever.
Indiscriminate and illegal slaughter of sacrificial animals, whether at houses or by unauthorised street butchers, can pose health hazards and expose a person to the risks of Crimean-Congo Haemorrhagic fever, the Ministry of Health and Prevention (MoHAP) has warned.
KARACHI -- Medical and Health Services Department Karachi Metropolitan Corporation (KMC) has asked the Municipal Services KMC to launch a fumigation drive on daily basis to prevent citizens from catching deadly Crimean-Congo Haemorrhagic Fever (CCHF).
Crimean-Congo haemorrhagic fever outbreak in Middle Anatolia: a multicentre study of clinical features and outcome measures.
Pakistan's first case of Crimean-Congo haemorrhagic fever (CCHF), commonly known as Congo virus , has been reported on Sunday as a 35-year-old woman hailing from Orangi Town of Karchi tested positive at the Jinnah Postgraduate Medical Centre (JPMC).
Crimean-Congo haemorrhagic fever (CCHF) is a tick-borne zoonosis caused by a Nairovirus (family: Bunyaviridae) and is endemic in Africa, the Middle East, Asia and southern Europe.
Madam, I find it necessary and vital to share with you a case of Crimean-Congo haemorrhagic fever (CCHF)proven on PCR who came from Aga Khan University Hospital after leaving against medical advice to the Memon Medical Institute Hospital's Emergency Room on 5th June 2018.
Field and laboratory investigation of Crimean-Congo haemorrhagic fever virus (Nairovirus, family Bunyaviridae) infection in birds.