Successful management of an extreme example of neonatal hyperprostaglandin-E syndrome (Bartter's syndrome) with the new cyclooxygenase-2 inhibitor
Ozono et al., "Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor
, on the development of rat urinary bladder carcinomas initiated by N-butyl-N(4-hydroxybutyl) nitrosamine," Cancer Research, vol.
The use of selective cyclooxygenase-2 inhibitors
(coxibs)  and traditional nonsteroidal antiinflammatory drugs (tNSAIDs) has been documented to increase the incidence of myocardial infarction and stroke (1-3).
Cardiovascular thrombotic events in arthritis trials of the cyclooxygenase-2 inhibitor
and cardiovascular risk in a nationwide cohort study after the withdrawal of Rofecoxib.
The cyclooxygenase-2 inhibitor
celecoxib is also in the skin can cer race.
A cyclooxygenase-2 inhibitor
impairs ligament healing in the rat.
Celecoxib, the only cyclooxygenase-2 inhibitor
left on the U.S.
suppressed angiotensin II-induced secretion of thromboxane B2 in human aortic endothelial cells
For patients who are at GI risk, a selective cyclooxygenase-2 inhibitor
is recommended, he said.
For instance, 17% were taking an NSAID or a cyclooxygenase-2 inhibitor
, 41% were taking aspirin or clopidogrel, and 24% were on Coumadin or enoxaparin.
has announced that it will pay $4.85 billion into a fund to settle claims that its cyclooxygenase-2 inhibitor
rofecoxib (Vioxx) was responsible for causing myocardial infarction and stroke in patients who took the drug for pain.