cytotoxic T cell

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cytotoxic T cell

[¦sīd·ə‚täk·sik ′tē ‚sel]
(immunology)
A type of T cell which protects against pathogens that invade host cell cytoplasm, where they cannot be bound by antibodies, by recognizing and killing the host cell before the pathogens can proliferate and escape.
References in periodicals archive ?
Vaccinia virus-specific CD8+ cytotoxic T lymphocytes in humans.
Rotavirus-specific cytotoxic T lymphocytes appear at the intestinal mucosal surface after rotavirus infection.
The authors demonstrated that the anti-tumor effect of talabostat appears to involve tumor-specific cytotoxic T lymphocytes (CTL) and protective immunological memory.
The researchers believe that cytotoxic T lymphocytes play a role in the pathogenesis of emphysema.
Next, they isolated the cytotoxic T lymphocytes, killer white cells that destroy tumors.
The authors had previously found that telomere loss in cytotoxic T lymphocytes (CTLs), the cells responsible for killing HIV-infected cells, was accelerated in AIDS patients, and contributed to the loss of anti-HIV activity that occurs during disease progression.
The Phase II combination study in newly diagnosed, metastatic RCC patients with unfavourable prognosis demonstrated decreases in T regulatory cells, along with a concurrent expansion of CD28+memory cytotoxic T lymphocytes (CTL).
are studying the action of cytotoxic T lymphocytes, cellular immune responders that attack foreign or infected cells.
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