Impaired function of NK cells and cytotoxic T-cells
is characteristic for both genetic and acquired forms of HLH.
Subcutaneous panniculitis-like T-cell lymphoma is a rare cytotoxic T-cell
lymphoma that can be misdiagnosed as a benign panniculitis due to histologic similarities between the 2 entities.
NK cells, unlike cytotoxic T-cells
, do not require to be 'taught' to recognize cancer cells, they naturally find and destroy cancer cells.
The research demonstrated that the Geron compounds increased the proliferative capacity of cytotoxic T-cells
and their ability to produce a virus-fighting molecule, gamma Interferon.
Antibodies bind to and neutralize infectious viral particles while cytotoxic T-cells
attack host cells, which synthesize the virus, before the virus is released into the circulation.
The chicken's immune system produces cytotoxic T-cells
whose function it is to target and destroy infected cells," explains Lillehoj.
Moreover, this was the first time an adjuvant has shown the ability to induce CD8+ cytotoxic T-cells
The mechanism is unclear, but extrapolating from familial form, deranged cytokine interaction between histiocytes, cytotoxic T-cells
and natural killer (NK) cells due to defective perforin[sup.
He noted that immune responses based on production of specific cells, known as cytotoxic T-cells
, have been largely neglected in evaluating the efficacy of flu vaccinations.