cytotoxic T cell

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cytotoxic T cell

[¦sīd·ə‚täk·sik ′tē ‚sel]
(immunology)
A type of T cell which protects against pathogens that invade host cell cytoplasm, where they cannot be bound by antibodies, by recognizing and killing the host cell before the pathogens can proliferate and escape.
References in periodicals archive ?
Impaired function of NK cells and cytotoxic T-cells is characteristic for both genetic and acquired forms of HLH.
Subcutaneous panniculitis-like T-cell lymphoma is a rare cytotoxic T-cell lymphoma that can be misdiagnosed as a benign panniculitis due to histologic similarities between the 2 entities.
NK cells, unlike cytotoxic T-cells, do not require to be 'taught' to recognize cancer cells, they naturally find and destroy cancer cells.
The research demonstrated that the Geron compounds increased the proliferative capacity of cytotoxic T-cells and their ability to produce a virus-fighting molecule, gamma Interferon.
Antibodies bind to and neutralize infectious viral particles while cytotoxic T-cells attack host cells, which synthesize the virus, before the virus is released into the circulation.
The chicken's immune system produces cytotoxic T-cells whose function it is to target and destroy infected cells," explains Lillehoj.
Moreover, this was the first time an adjuvant has shown the ability to induce CD8+ cytotoxic T-cells in humans.
The mechanism is unclear, but extrapolating from familial form, deranged cytokine interaction between histiocytes, cytotoxic T-cells and natural killer (NK) cells due to defective perforin[sup.
He noted that immune responses based on production of specific cells, known as cytotoxic T-cells, have been largely neglected in evaluating the efficacy of flu vaccinations.
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