treatment significantly increased serum E2 concentration compared to CTRL, and both FSHP4 and NA-FSHP4 treatments restored an E2 level statistically similar to the CTRL.
Nonetheless we did not measure DHEA
level and therefore we exclude the possibility of altered DHEA
in these patients.
Recommended dosage of micronized DHEA
is 25 mg three times daily.
Another study, in which authors integrated data from four phase 3 clinical trials of postmenopausal women with vulvovaginal atrophy treated with vaginal DHEA
(n = 723) or placebo (n = 266) for 12 weeks, analyzed serum steroid levels measured at Day 1 and Week 12 by liquid chromatography-tandem mass spectrometry.
Symptom Checklist-90-R Pain Items and Serum DHEA
supplementation was associated with fewer miscarriages and significantly more live births in infertile women with normal ovarian reserve in a recent blinded RCT (Reprod.
There was a weak but statistically significant positive correlation between BAI score and serum DHEAS levels (Pearson r=0.
Studies show that several beneficial effects associated with DHEA
treatment are provided from an improvement in body oxidative balance (ARAGNO et al.
There is a clear correlation between the lack of ability to produce DHEA
through oxidation in the blood and the degree of cognitive impairment found in Alzheimer's disease," said senior author Dr Vassilios Papadopoulos, who is director of the institute.
Professor Clive Ballard, director of research at the Alzheimer's Society, said: "Research about the blood test for DHEA
is in the very early stages and much more research is now needed to confirm these findings and to better understand whether the DHEA
blood test could provide useful information about the diagnosis or progression of Alzheimer's disease.
EndoCeutics will head the Phase III clinical studies of DHEA
against vaginal atrophy and sexual dysfunction.
Q I've been taking DHEA
to improve my libido, but my cardiologist wants me to stop, as he thinks it may be bad for my heart.