hybridization probe

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Related to DNA probe: PCR, DNA fingerprinting

hybridization probe

[‚hī·brəd·ə′zā·shən ′prōb]
(cell and molecular biology)
A small molecule of deoxyribonucleic acid or ribonucleic acid that is radioactively labeled and used to identify complementary nucleic acid sequences by hybridization.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Development and application of cloned DNA probes for a mycoplasmalike organism associated with sweet potato witches'-broom.
In agreement with our data, others have also found a good correlation between DNA probes and the BANA Test in untreated subjects, i.e comparable with time T0.
In addition, two oligonucleotide DNA probes were designed to target the 18S rRNA gene sequence of the parasite, facilitating detection in situ in crustacean tissues.
Clinicians were not as accurate as the DNA probe test in diagnosing vaginal infections.
A third single-stranded DNA probe ("3") is included, which also shares half complementarity to the analyte (thereby binding to the localized, bound analyte) and on its other end, binds a highly branched, tree-like structure which has many labeled arms as its "branches" ("4").
The company has the infrastructure and scientific know-how needed to integrate Cancer Genetics' DNA probe manufacturing and FHACT test for the management of cervical cancer into the Indian market, the buyer noted.
Experimental parameters including the amount of DNA probe in the test zone, amount of gold-Nanoparticle conjugate on the conjugate pad, the components of the running buffer as well as the pretreatment conditions of the sample pad were optimized systematically.
A 20-bp 5'-biotinylated B19 DNA probe (5'-biotin-ATGCAGCTACAACTTCGGAG-3') was used.
In 502 visits (33%), physicians used a DNA probe without a Gram stain, 68 visits (5%) included a Gram stain without a DNA probe, and 941 visits (62%) included both a Gram stain and a DNA probe to detect sexually transmitted infections.
The results of his randomized study of 3,460 Pap smears and 5,535 combination DNA probe assays appear to refute longstanding concerns that gel lubrication could interfere with cervical microbiology or Pap smear findings.
causing significant tissue damage in juvenile Korean Manila clams, Parasite taxonomic verification was made using a genus-Perkinsus SSUrRNA gene-specific DNA probe for in situ hybridization.
The company's GeneChip system consists of disposable DNA probe arrays containing gene sequences on a chip, reagents for use with the probe arrays, a scanner, and other instruments to process the probe arrays and software to analyze and manage genetic information.
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