histoplasmosis(redirected from Darling disease)
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histoplasmosis:see fungal infectionfungal infection,
infection caused by a fungus (see Fungi), some affecting animals, others plants. Fungal Infections of Human and Animals
Many fungal infections, or mycoses, of humans and animals affect only the outer layers of skin, and although they are sometimes
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a fungal disease (mycosis) that attacks primarily the reticuloendothelial system in man and animals.
Histoplasmosis is found mostly in tropical countries. The causative agent is the parasitic fungus Histoplasma, which can survive for long periods in soil. There is no direct indication that histoplasmosis is transmitted from one person to another; it may be transmitted by mites. It occurs in acute, subacute, chronic, disseminated, or localized forms. Histoplasmosis is manifested by enlargement of the liver, spleen, and lymph nodes, fever, and anemia. It involves the skin and mucous membranes (hemorrhages and occasionally ulcerative lesions) in half the patients. Bloody expectoration occurs in pulmonary histoplasmosis. Supportive and radiation therapy, medication, and surgical intervention are used in treatment.