Food-derived Cbl species undergo dealkylation
or decyanation where their original cobalt-attached [beta] ligands are replaced with methyl or adenosyl groups to form active Cbl species, and dealkylation
of alkylcobalamins requires the thiolate of GSH for nucleophilic displacement .
mechanism of plant sterols to cholesterol.
Aging is associated with dealkylation
(the removal of alkyl group, an organic molecule made up of chains of carbon and hydrogen atoms joined by single bonds) by C-O or P-O fission (Beauregard et al.
The conversion of toluene increased with decreasing the amount of toluene in the feed, from toluene: methanol molar ratio of 8:1 to 1:2, and benzene (from disproportionation of toluene and/or toluene dealkylation
) decreased from 7.8% to 0.0.
Decker, "Kinetic, equilibrium, and spectroscopic studies on dealkylation
("aging") of alkyl organophosphonyl acetyl-cholinesterase.
Once this single MDF is replaced with four mass defect filters that cover specific regions of the Phase I and II metabolites of the parent and its dealkylation
product, SN-38, the chromatogram became much cleaner (Figure 3c).
This behavior is ascribed to the increase in secondary cracking reaction such as dehydrogenation of components of heavy fraction of the produced oil and subsequent coke deposition, the dealkylation
, reforming reactions are also possible candidates.
on a manganese oxide surface.
The overall importance of persistent [Hg.sup.2+] in the brain stems from the fact that recent studies showed that dealkylation
of Hg in the brain is not necessarily a detoxification process (40-44).
7,253,324, protecting the process for the synthesis of biologically active polyphenolic compounds by novel dealkylation
. This process of aromatic poly o-demethylation is applicable in the manufacturing of polyphenols, such as resveratrol, oxyresveratrol and gnetol.
Dehydrogenation and dealkylation
reactions bring about the fusion of large aromatic structures into highly organized shapes, similar to the parallel layers of condensed planer [C.sub.6] rings that constitute the graphite crystallite (Singh, 1991).