2 Histopathologically, lesions are composed of loose fibrous connective tissue stroma having stellate-shaped fibroblasts with areas of myxoid degeneration resembling dental papilla
covered by peripheral columnar epithelium which itself resembles inner enamel epithelium (covering of columnar epithelium is absent in odontogenic myxomas and odontogenic fibromas).
Wang et al., "Immortalized mouse floxed Bmp2 dental papilla
mesenchymal cell lines preserve odontoblastic phenotype and respond to BMP2," Journal of Cellular Physiology, vol.
Our present data showed, amelogenin in a 53.29 % in rough endoplasmic reticulum in enamel organ and dental papilla
in later stages; which means the start of the amelogenin synthesis occurring.
(b) Histopathology shows odontogenic epithelium with peripheral palisading nuclei resembling ameloblast-like cells and loosely arranged central cells, identical to stellate reticulum, embedded in a myxoid cell-rich stroma resembling the dental papilla
. Focal areas of enamel and dentin are also present.
The Inductive Role of the Dental Papilla
. Journal Embryologic Experimental Morphology 1970; 24:173-186.
Focal failure of internal enamel epithelium development, aggressive and rapid proliferation of a portion of the internal enamel epithelium occupying the dental papilla
, external forces affecting the tooth germ during growth and also, genetic factors have been suggested to be the cause.
In our study, during the 16-day intrauterine life, the use of propineb was found effective on odontoblast cell hyperplasia, cell infiltration in the dental papilla
, and degeneration in the mesenchymal cells of the outer enamel (Fig.
Ameloblastic fibromas are a rare variety of benign odontogenic tumors composed of proliferating odontogenic epithelium embedded in a cellular ectomesenchymal tissue resembling dental papilla
. (1) It was first described by Kruse in 1891 and later classified as a separate entity by Thoma and Goldman in 1946.
Fletcher, "The effect of the distance from the contact point to the crest of bone on the presence or absence of the interproximal dental papilla
," Journal of Periodontology, vol.
The wax-up model was duplicated in stone and 0.01 inch hot-mounted thermoplastic sheet was pressed over it and cut back to the level of gingival margins labially/buccally and palatally/lingually exposing the dental papilla
. That will serve two purposes; to prevent locking of the acrylic material in the interdental spaces and to allow the gingival margins of teeth to act as reference point on which we need to stop at when placing the acrylic-loaded splint.
It is thought to occur during morphodifferentiation stage as a result of outward folding of inner enamel epithelial cells (precursors of ameloblasts) and transient focal hyperplasia of mesenchymal dental papilla
(precursors of odontoblasts) or a combination of genetic and environmental factors (multifactorial) (2).