Deoxyribonuclease


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Related to Deoxyribonuclease: Deoxyribonucleic

deoxyribonuclease

[dē¦äk·sē‚rī·bō′nü·klē‚ās]
(biochemistry)
An enzyme that catalyzes the hydrolysis of deoxyribonucleic acid to nucleotides. Abbreviated DNase.

Deoxyribonuclease

 

an enzyme that catalyzes the hydrolysis of deoxyribonucleic acid. It belongs to the class of hydrolases, to the group of phosphatases. It is present in the cells of animals, plants, and microorganisms (except certain viruses).

References in periodicals archive ?
Lazarus RA, Wagener JS (2007) Recombinant Human Deoxyribonuclease I".
The isolates were identified based on the litmus milk test, gelatinase, deoxyribonuclease (DNase), lecithinase and fermentation of glucose and lactose (Holt et al.
Typical colonies (black surrounded by clear zones) were tested for coagulase activity using rabbit plasma after activation by overnight incubation in Brain Heart broth, at 35[degrees]C, and tested for deoxyribonuclease (DNAse) activities by using DNAse agar, and revealed by hydrochloric acid (HCl) at 2%.
Selective media such as mannitol salt agar and deoxyribonuclease (DNase) agar can differentiate the species of Staphylococcus.
The use of a new method to observe the kinetics of deoxyribonucleic acid degradation by deoxyribonuclease I, deoxyribonuclease II, and Escherichia coli endonuclease I.
On January 9, 2007, ASVL sent the unidentified viral isolate to CDC, where the isolate was evaluated using two pathogen-discovery strategies: a pan-herpes virus polymerase chain reaction (PCR) test and a deoxyribonuclease sequence-independent, single-primer amplification (DNase-SISPA) sequencing method, * in which a specimen is treated with DNase, followed by nucleic acid extraction, random amplification, restriction enzyme digestion, and SISPA of the restriction fragments.
Although serologies in most patients were positive for both antistreptolysin O and deoxyribonuclease B antibodies, indicating [beta]-hemolytic streptococci infection, some were positive for just one or the other antibody.
Although serologies in most patients were positive for both antistreptolysin O and deoxyribonuclease B antibodies, indicating [beta]hemolytic streptococci infection, some were positive for just one or the other antibody.
Risk factors noted in case-control studies include high-dose pancreatic enzyme replacement therapy, younger age (2-13 years), history of gastrointestinal complications (DIOS, meconium ileus, colitis), prior gastrointestinal surgery, use of histamine H2-receptor blockers, corticosteroids, and recombinant human deoxyribonuclease.
There were sufficient data to reject--or at least doubt--the efficacy of several commonly used treatments: aerosolized ribavirin, antibiotics, nebulized furosemide, intravenous RSV immunoglobulin (RSV IG) used for treatment rather than prophylaxis, inhaled interferon-a, and nebulized recombinant human deoxyribonuclease.
1) Deoxyribonuclease (DNase I) sensitive perinuclear antineutrophil cytoplasmic autoantibody (pANCA) associated with IBD.

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