Deoxyribose


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Related to Deoxyribose: phosphodiester bond

Deoxyribose

A nucleic acid constituent (see illustration) of all animal, microbial, and plant cells; also known as 2- d -deoxyribose. Deoxyribose is enzymically formed in living cells by reduction of ribonucleoside di- or triphosphate. The four deoxyribose nucleotides, containing adenine, guanine, cytosine, and thymine, are the major constituents of the deoxyribonucleic acids (DNA), which control the hereditary characteristics of every living organism. See Deoxyribonucleic acid (dna), Nucleic acid, Ribose

Formulas of 2- D -deoxyribose (α- D -2-deoxyribofuranose)enlarge picture
Formulas of 2- D -deoxyribose (α- D -2-deoxyribofuranose)

Deoxyribose

 

a carbohydrate belonging to the deoxy-sugars. Part of the deoxyribonucleic acids, it consists of crystals and has a molecular weight of 134.1 and a melting point of 78°-82° C. Its structural formula is

deoxyribose

[dē¦äk·sē′rī‚bōs]
(biochemistry)
C5H10O4 A pentose sugar in which the hydrogen replaces the hydroxyl groups of ribose; a major constituent of deoxyribonucleic acid.
References in periodicals archive ?
* RNA contains a ribose sugar hydroxylated at the second carbon, while DNA contains a deoxyribose sugar protonated (hydrogen atom) at the second carbon
One of the preferred targets for [H.sub.2][O.sub.2] is the DNA; it produces single- or double-stranded DNA breaks as well as DNA cross links, in addition to purine, pyrimidine, or deoxyribose modifications [13].
Halliwell, "The deoxyribose assay: an assay both for 'free' hydroxyl radical and for site-specific hydroxyl radical production," Biochemical Journal, vol.
Folin-Ciocalteu reagent, sodium carbonate, gallic acid, rutin, aluminium chloride, sodium nitrate, sodium hydroxide, 2,2-diphenyl-1-picrylhydrazyl (DPPH), trichloroacetic acid, potassium ferricyanide, sodium acetate buffer, neocuproine, deoxyribose, EDTA, potassium phosphate buffer, hydrogen peroxide, ascorbic acid, TBA, 2,4,6 tripyridyl-s-triazine (TPTZ), ferric chloride, HCl, ammonium molybdate, sodium phosphate, sulfuric acid, ammonium thiocyanate, and all other chemicals used were of analytical grade.
ROS-induced DNA damage can result in DNA single- or double-strand breakage, base modifications, deoxyribose modifications, and DNA cross-linking.
celtidifolius showed antioxidant properties, due to scavenged superoxide anions, inhibited deoxyribose degradation and lipidic peroxidation in vitro, and antiedematogenic effects by reducing paw edema induced by carrageenan in rats (Nardi et al., 2003).
Free radicals can attack DNA at C4 of deoxyribose generating products as propenal, which react with 2-thiobarbituric acid and produce the TBARS formation [40].
Hydroxyl radical was produced in the presence of 20 [micro]M Fe[Cl.sub.3], 1.4mM [H.sub.2][O.sub.2], 2.8 mM deoxyribose, 100 [micro]M EDTA, and 100 [micro]M ascorbate, in 10 mM phosphate buffer, pH = 7.4, as was published earlier (Sanz et al., 1994).
For antioxidant analysis, reagents were used as follows: dimethyl thiourea (DMTU), nordihydroguaiaretic acid (NDGA), ascorbic acid, histidine, xylenol orange, ammonium iron (II) sulfate hexahydrate, N,N-dimethyl-4nitrosoaniline (DMNA), catalase, xanthine, xanthineoxidase, nitroblue tetrazolium (NBT), deoxyribose, and butylated hydroxytoluene (BHT) were from Sigma Aldrich (St.