Dermatomyositis


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dermatomyositis

[dər¦mad·ō‚mī·ə′sīd·əs]
(medicine)
An inflammatory reaction of unknown cause involving degenerative changes of skin and muscle.

Dermatomyositis

 

a systemic disease chiefly involving the skin, muscles, and nerves.

Dermatomyositis was first described by the German physician E. Wagner and (independently) by the German physician H. Unverricht in 1887 and called acute progressive poliomyositis. In 1891, Unverricht suggested the name “dermatomyositis.” The disease has been little studied, and there is no consensus regarding its origin and development. Dermatomyositis may occur in acute or chronic form; in the latter there are intervals of varying duration (remissions) between exacerbations. The manifestations are extremely variable. The commonest are muscular pains, tension in some muscle groups (especially on movement), reddening of certain parts of the skin (most often on the face near the eyes, cheeks , and nose), peeling, and dilatation of blood vessels in the skin (telangiectasia). Hormonal preparations, antibiotics, antimalarial agents, antihistamines and desensitizing preparations, and vitamins are used in treatment. Dermatomyositis patients should be kept under clinical observation.

G. IA. SHARAPOVA and I. N. VEDROVA

References in periodicals archive ?
Polymyositis and dermatomyositis. Lancet 2003;362:971-82.
Interstitial lung disease in polymyositis and dermatomyositis: clinical features and prognosis as correlated with histologic findings.
We prescribed only one dose of Aurum metallicum 30C out of concern for an aggravation of Carolyn's dermatomyositis. Three weeks later she reported:
Pearson, "Computer-assisted analysis of 153 patients with polymyositis and dermatomyositis," Medicine, vol.
Phillippe, "Primary idiopathic polymyositis and dermatomyositis complicating pregnancy: diagnosis and management," Obstetrical & Gynecological Survey, vol.
Ramji, "NXP-2 positive dermatomyositis: a unique clinical presentation," Case Reports in Rheumatology, vol.
Keywords: Dermatomyositis, Amyopathic dermatomyositis, Urticaria Dermatomyositis sine myositis.
However, specific forms of myositis like dermatomyositis and polymyositis occur when the body's immune system turns against its own muscles, damaging the muscle tissue in the process.
(1) Dermatomyositis (DM) and polymyositis (PM) are the two main types in which the incidence and prevalence of DM is 1.4 and 5.8 cases per 100,000 persons in a recent study in U.S.
Patients with serum anti-melanoma differentiation-associated gene 5 autoantibodies (anti-MDA5) are related to amyopathic dermatomyositis, especially in Asians.
1) was sent to the laboratory from a 64-year-old male patient with stage IV non-small- cell lung cancer and paraneoplastic dermatomyositis. The results for electrolytes, glucose, pH, pC[O.sub.2], and p[O.sub.2] were unremarkable, but the instrument could not generate co-oximetry (e.g., oxyhemoglobin) results.
| Case study: Lee Everett-Pride, from Swansea, was involved in one of the ABMU Patients Know Best pilots as her 12-year-old son Sam has juvenile dermatomyositis.