desmosome

(redirected from Desmosomal cadherins)
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desmosome

[′dez·mə‚sōm]
(cell and molecular biology)
References in periodicals archive ?
The cadherin superfamily is made up of the classical cadherins, desmosomal cadherins, protocadherins, and other cadherin-like proteins that do not fit into any of these subfamilies (Nollet et al.
Whereas the cadherins in most AJs are linked to the actin cytoskeleton through [alpha]-and [beta]-catenin, desmosomal cadherins recruit the armadillo proteins plakoglobin and plakophilin-1, which are vertebrate-specific gene duplications related to [beta]-catenin and are linked to the intermediate filament cytoskeleton either directly or via the linker protein desmoplakin (Schneider et al.
2) They are histologically characterized by suprabasilar acantholysis and immunopathologically characterized by autoantibodies to desmosomal cadherins.
In desmosomes, two classes of desmosomal cadherins, the desmogleins and desmocollins, bind to the [Beta]-catenin-related protein called plakoglobin.