(5.21 g, 0.005 M) obtained was added with stirring to an aqueous slurry of potassium chloride (0.52 g, 0.005 M).
To test it, we converted free energies of formation of both (HB-O and HB-N) forms of competing diastereoisomers
to percentage distribution.
It is noteworthy that the majority diastereoisomer
formed was the same in the case of the reaction catalyzed by TEBAC.
Huang, Complete NMR spectral assignments of two new iridoid diastereoisomers
from the flowers of Plumeria rubra L.
However, indirect chiral separation can be achieved by converting enantiomers to diastereoisomers
via derivatization reaction of the targeted compounds with optically pure chiral derivatizing agents (CDAs) .
2-methylcitrate elutes as a double peak, representing diastereoisomers
. Propionylglycine excretion is variable in PA.
This compound is a racemic mixture, and investigations have demonstrated that both diastereoisomers
have similar activity in vitro against Plasmodium.
Importantly, until recently SAM-e's benefit was virtually unknown, due to it is extreme instability at temperatures above 0[degrees] C, or in the presence of moisture, "both as degradation of the active ingredient intended as the sum of the two diastereoisomers
, and as transformation of active (SS)-(+)-S-adenosyl-L-methionine into inactivate (RS)-(+)-S-adenosyl-L-methionine (racemisation of the substance)." (13)
Silybin makes up more than 50% of silymarin and is made up of a mixture of two diastereoisomers
, silybin A and silybin B.
Xie et al., "Determination of hexabromocyclododecane diastereoisomers
in Sargassum fusiforme and comparison of the extraction efficiency of ultrasonication, microwave-assisted extraction, Soxhlet extraction and pressurised liquid extraction," Journal of Separation Science, vol.