diastereomer


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Related to diastereomer: anomer

diastereomer

[¦dī·ə¦ster·ē′ō·mər]
(organic chemistry)
References in periodicals archive ?
When we examined the TBECH diastereomer binding activities, we found that 50:50 TBECH-[gamma][delta] binds to the AR with 22% of DHT's binding affinity, whereas for 50:50 TBECH-[alpha][beta] we found a relative binding affinity (RBA) of 6%.
This difference in affinity may have been attributable to a stereoselectivity bias from the FBP toward the unnatural diastereomer of the racemic 5mTHF.
The stability of the derivatives was tested by regression analysis in which the absolute peak areas of each diastereomer of AM and MA at each concentration were plotted vs injection time.
A solution of the diastereomer (6.81 g, 0.005 M) in a minimum amount of water was added to potassium chloride (0.52 g, 0.005 M) with vigorous stirring.
Residue was purified by column chromatography (silica gel, EtOAc/C[H.sub.3]OH 1: 4) affording product 2i (one diastereomer) as a white solid (40 mg, 31%; mp > 240[degrees]C).
The major diastereomer 7a upon treatment with Bocanhydride and TEA in DCM using catalytic amount of DMAP at 0[degrees]C to rt produced carbamate 8 with 79% yield.
It is known that silymarin elicited partial ER activation and silybin B were probably responsible for a majority of the weak ER-mediated activities of silymarin, whereas, its diastereomer, silybin A, was found to be inactive [173].
Covaci, "Causes of variability in concentrations and diastereomer patterns of hexabromocyclododecanes in indoor dust," Environment International, vol.
Spatial diastereomer patterns of hexabromocyclododecane (HBCD) in a Norwegian fjord.
Of all the forms, the studies of its threo diastereomer revealed that d-threo isomer has been found to be more active and also showed significant metabolic difference than l-threo enantiomer.
Since this reaction introduces two chiral carbons into the product, the cis alkenes are known to form a racemic mixture, and the trans isomer forms a stereospecific meso diastereomer. According to the literature (Mathai et al., 1956), addition of bromine to maleic acid in chloroform solvent occurs in the dark at room temperature but takes several days.