dicyclohexylcarbodiimide

dicyclohexylcarbodiimide

[dī¦sī·klō¦hek·səl¦kär·bō′dī·ə·məd]
(organic chemistry)
C13H22N2 Crystals with a melting point of 35-36°C; used in peptide synthesis. Abbreviated DCC; DCCI.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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(5) 2,2,6,6-Tetramethylpiperidinyloxy benzoic acid (3.4 g, 9.4 mmol) was coupled with [beta]-CD ([beta]-cyclodextrin 8.6 g, 7.0 mmol) using dicyclohexylcarbodiimide (DCC 2.1 g, 9.5mmol) in DMF (dimethylformamide 100 mL).
(25) Modification of Glu190 of the [beta] subunit of T[F.sub.1] (from thermophilic Bacillus PS3) with dicyclohexylcarbodiimide (DCCD) (26) and substitution of this residue by glutamine (27) resulted in complete loss of the activity.
N, N'- dicyclohexylcarbodiimide (DCC) (34.05 g, 0.165 mol) dissolved in ethyl acetate (60 mL) was added to the cooled ethyl acetate solution at 0[degrees]C.
Folate (FA), dicyclohexylcarbodiimide (DCC), N-hydroxysuccinimide (NHS), dioxotetrahydrofuran, and 4-dimethylaminopyridine (DMAP) were purchased from Aladdin Industrial Co.
Various methods have already been reported for the synthesis of indole-3-acetamides including the usage of various coupling reagents like DCC (N,N- dicyclohexylcarbodiimide).[11] However, the use of DCC results in the production of o-acylurea which may undergo rearrangement leading to the formation of un-reactive intermediate N-acylurea consequently yield is reduced.
Stannous octoate (Sn-oct, Sigma), Dicyclohexylcarbodiimide (DCC, FLUCA), 4-(dimethyl amino) pyridine (DMAP, FALUCA), dichloromethane (DCM), Dimethyl Sulphoxide (DMSO) and other chemicals used in the current investigation were of HPLC grade procured from Ranbaxy Fine Chemicals Ltd, India.
N,N2 dicyclohexylcarbodiimide, an inhibitor of proton translocators, inhibited the NADPH '!
Mechanism of inhibition of mitochondrial adenosine triphosphatase by dicyclohexylcarbodiimide and oligomycin: relationship to ATP synthesis.
Compound 5a (9.8 mg; 1.9 [micro]mol) and N-hydroxysuccinimide (2.2 mg; 1.9 [micro]mol) were dissolved in 100 [micro]L of anhydrous DMF, and dicyclohexylcarbodiimide (3.9 mg; 1.9 [micro]mol) was added last.
Briefly, to a 0.2mL solution of PMLA (25mg, 0.22 mmol equivalent of malic acid) in acetone was added a mixture of N-hydroxysuccinimide (NHS, 25 mg, 0.22 mmol) and dicyclohexylcarbodiimide (DCC, 47 mg, 0.22 mmol) in 0.2 mL DMF.
Synthesis of fatty acid anhydrides by reaction with dicyclohexylcarbodiimide. J Lipid Res 1966;7:174-95.