human papillomavirus

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human papillomavirus

(HPV), any of a family of more than 100 viruses that cause various growths, including plantar wartswart,
circumscribed outgrowth of the skin caused by a filterable virus that is readily transmitted. Warts may appear anywhere on the skin but are most common on the hands.
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 and genital warts, a sexually transmitted diseasesexually transmitted disease
(STD) or venereal disease,
term for infections acquired mainly through sexual contact. Five diseases were traditionally known as venereal diseases: gonorrhea, syphilis, and the less common granuloma inguinale, lymphogranuloma venereum, and
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. Genital warts, sometimes called condylomata acuminata, are soft and often occur in clusters. They can occur internally or externally, but even in the absence of warts the virus may be present and transmittable. Problems can result from untreated warts, which can grow quite large, or, in rare cases, from infection of an infant during delivery. In addition, about a dozen strains of HPV are associated with cancercancer,
in medicine, common term for neoplasms, or tumors, that are malignant. Like benign tumors, malignant tumors do not respond to body mechanisms that limit cell growth.
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 of the cervix, vulva, vagina, penis, and anus, and HPV 16 has been shown to be associated with some forms of Kaposi's sarcoma (see AIDSAIDS
or acquired immunodeficiency syndrome,
fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981.
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) and throat cancer.

Transmission of HPV strains is often the result of sexual contact, but it can also occur as the result of any skin-to-skin contact involving the mouth or genitals. Detectable warts can be or removed, usually by chemicals, freezing, or laser, but often recur. Intralesional alpha interferon has been effective in the treatment of genital warts. A vaccine approved by the Food and Drug Administration in 2006 can protect a woman against those strains that cause most cases of cervical cancer and genital warts, and a study has shown it may also protect against related throat cancers. HPV vaccination is now recommended for both girls and boys beginning at 11 to 12 years of age.

human papillomavirus

[¦yü·mən ‚pap·ə′lō·mə ‚vī·rəs]
(medicine)
One of a family of more than 100 different viruses, most commonly spread via sexual contact, that cause warts on the hands and feet and in the genital area; several types are associated with premalignant and malignant changes in the cervix. Abbreviated HPV.
References in periodicals archive ?
The Digene Hybrid Capture 2[R] (Qiagen, Germany) was utilized to detect 13 types of HR-HPV infection according to the manufacturers' instructions.
Participating laboratories could choose from 1 of 4 modules based on the medium most commonly used for HPV testing in their laboratories: Digene (CHPVD), SurePath (CHPVK), ThinPrep (CHPVM), or mixed.
Digene Farrar was in New York City, launching the modeling career she'd always dreamed of.
Digene Corporation Announces FDA Clearance for CT/GC Test Rapid Capture System Application.
The Federal Trade Commission recently prevented Cytyc Corporation, now a part of Hologic, from acquiring Digene Corporation, now a part of Qiagen, due to competitive concerns regarding the HPV business.
Comparison of the Digene Hybrid Capture 2 assay and Roche AMPLICOR and LINEAR ARRAY Human Papillomavirus (HPV) tests in detecting High-Risk HPV genotypes in specimens from women with previous abnormal Pap smear results.
This panel includes the digene HPV Test, which is regarded as a "gold standard" in testing for high-risk types of human papillomavirus (HPV), the primary cause of cervical cancer, as well as a broad suite of solutions for infectious disease testing and companion diagnostics.
The cytological and histological examinations were done by the local teaching hospital's laboratories, while the HPV tests were analysed by means of PCR amplification by the Digene Corporation in Gaithersburg, Maryland, USA.
During April of 1933 and 1934 she visited the Lake and recovered specimens of a digenetic trematode (digene) from the intestines of three species of turtles (Table 1).
(Germantown, Maryland), marketed by Digene. (15) This in vitro nucleic acid hybridization assay can detect 13 high-risk HPV serotypes in cervical specimens using Hybrid Capture 2 technology with signal amplification and chemiluminescent detection.
[4] Grigore Georgiu, Natiune, cultura, identitate, Bucuresti, Editura Digene, 1997, p.77.