dimerization

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dimerization

[‚dī·mər·ə′zā·shən]
(chemistry)
A chemical reaction in which two identical molecular entities react to form a single dimer.
References in periodicals archive ?
The starlet sea anemone Nematostella vectensis has at least two [alpha] integrin subunits and four [beta] integrin subunits available to dimerize and bind to the extracellular matrix or mediate sperm-egg interactions.
59),60) On the other hand, we have found that diaminosilylene 63 generated by the photolysis of silacyclopropene 64 is marginally stable in solution and dimerizes to the corrresponding disilene-type dimer 65 at low temperature (eq [27]).
The MAP kinase extracellular regulated kinase (ERK)1/2 activates the activator protein (AP)-1 transcription factor through phosphorylation of c-fos that can then dimerize with c-jun and bind to the AP-1 DNA binding site (Gilley et al.
UV light ([lambda] = 254 nm) can dimerize coumarin and its derivatives, and it also dedimerize them (18).
7,8) Chara myosin has the motor domain of the head with ATPase in the N-terminal region, followed by the neck consisting of six IQ motifs for binding of calmodulin or the calmodulin related protein as light chains, long [alpha]-helix to dimerize by forming the coiled-coil structure of the rod, and the globular tail in the C-terminal domain probably for binding with a cargo in order to transport it to its destination.
When cells are under oxidative stress, NRF2 and/or NRF1 dimerize with small Maf or other bZIP proteins in the nucleoplasm, and the heterodimer binds to the cis-acting element(s) called antioxidant response elements (AREs) in the promoters of target genes, leading to their transcriptional activation (Biswas and Chan 2010; Maher and Yamamoto 2010).
The claims in the ARIAD patent cover methods for controlling such cellular events using small-molecule pharmaceuticals that dimerize intracellular proteins.
As a consequence, it may be suggested that the isocyanate from the depolymerization, which is very reactive dimerize with evolution of carbondiimide (which is not observed while it is very reactive) and C[O.
From insects and butterflies an Ecd receptor was cloned which needs to dimerize with another partner--ultra spiracle (usp) - to initiate the genomic mechanisms which will lead to metamorphosis (Segraves, 1994; Yao et al.
These molecules crosslink or dimerize, have a higher molecular weight, and therefore cannot be extracted anymore by the analytical desorption technique.