Because dialkylsilylene 31 is sterically well protected and does not dimerize
to the corresponding disilene either in solution or in the solid state, tethering two dialkylsilylene moieties may be possible to give a stable tethered bissilylene.
Once cleaved, MUC1* dimerizes
with itself and other growth factor receptors through binding of a newly discovered ligand for MUC1*, called NM23.
Following activation,[sup] the monomeric EGFR dimerizes
, which further activates the intracellular kinase pathways and causes auto-phosphorylation of tyrosine to residue.
After that the dissociated Nrf2 is transferred to the nucleus where it dimerizes
with members of another b-zip family, the small Maf proteins (Maf-F, Maf-G, and Maf-K), binds to ARE of phase II genes, and translates detoxification enzymes such as glutathione synthetase (GSS), glutathione reductase (GR), Gpx, thioredoxin (TRX), thioredoxin reductase (TRR), and peroxiredoxin (PRX) to prevent the oxidative stress [73, 82].
This protein is a member of the epidermal growth factor receptor superfamily, which, when activated by ligand binding, dimerizes
and regulates intracellular signal transduction through the mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways.
with a protein called Max, to bind Enhancer Box sequences (E-boxes) and recruits view of the above findings it was important to determine the role of CDK2.
The androgen receptor is then translocated to the nucleus where it dimerizes
and can act as a DNA transcription factor for up to 1,532 genes such as prostate specific antigen (PSA).