Dimethylamine


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dimethylamine

[‚dī¦meth·əl′am‚ēn]
(organic chemistry)
(CH3)2NH Flammable gas with ammonia aroma, boiling at 7°C; soluble in water, ether, and alcohol; used as an acid-gas absorbent, solvent, and flotation agent, in pharmaceuticals and electroplating, and in dehairing hides.

Dimethylamine

 

a secondary acyclic amine, (CH3)2NH; a colorless gas with a sharp, unpleasant odor. Upon cooling it condenses readily to a colorless liquid. Melting point, −92.2°C; boiling point, 6.9°C. It is soluble in water and organic solvents; with acids it yields crystalline salts and undergoes acylation, alkylation, and nitrosation. It is formed upon putrefaction of proteins.

In industry, dimethylamine is prepared (with an admixture of trimethylamine) from methanol and ammonia, as well as from formaldehyde and ammonium chloride. It is used in organic synthesis (the Mannich reaction) to produce medicinal preparations (dicain, chlorpromazine, and so on), rocket fuel (dimethylhydrazine), and vulcanization accelerators.

References in periodicals archive ?
The natural occurrence of formaldehyde in fish, which might form as a result of the enzymatic breakdown of TMAO to FA and dimethylamine (DMA), also elevates the activity of other microorganisms in the fish [4, 8, 35].
The products dimethylamine and formaldehyde are then susceptible to form both intra- and intermolecular crosslinks with protein side chains.
First, the material was defrosted and embedded in T208 resin (Cristal[R], styrene monometer, MEK TGDM 50 catalyst and dimethylamine) in a proportion suitable for hardening for approximately three minutes.
[11] investigated the hydrothermal conversion of PEN in aqueous amine (methylamine, dimethylamine, and trimethylamine) solution, and demonstrated that the total yields of both monomers with trimethylamine (97.2%) were higher than those with methylamine (86.6%) and dimethylamine (89.8%).
to 2,4-D dimethylamine and its distribution in the Muda Plain, Peninsular Malaysia.
Classes of compounds detected by the NMR method included amino acids (alanine, asparagine, arginine, cysteine, glycine, glutamate, glutamine, homoserine, isoleucine, leucine, lysine, methionine, phenylalanine, sarcosine, serine, threonine, tyrosine, taurine, valine); alcohols (methanol and glycerol); ketones and fatty acid by-products (acetoacetate, acetate, 3-hydroxybutyrate, acetone, pyruvate, isobutyrate); sugar (glucose); other small molecule intermediates (o-phosphocholine, choline, n,n-dimethylglycine, citrate, creatine, lactate, methylhistidine, succinate, myo-inositol, dimethylamine, methylsuccinate, and 2-hydroxyisobutyrate).
Dimethylamine ([greater than or equal to]99.8%), allyldimethylamine (>99.0%), allyl chloride (>99.8%), allyl alcohol (>99.5%), and allyl aldehyde (>99.0%) were purchased from Sigma-Aldrich (USA).
[55] Citrate, glutamine, acetone, pyruvate, [beta]-hydroxyisobutyrate, acetoacetate, histidine, dimethylamine, and creatinine had a high diagnostic accuracy for the discrimination of AIH from PBC.
A number of metabolites were identified in the urine, including amino acids such as leucine, alanine, phenylalanine, glycine, and creatine; organic acids such as lactate, acetate, succinate, 2-oxoglutarate, citrate, hippurate, 2-hydroxyvalerate, and cis-aconitate; waste metabolites such as formate, allantoin, dimethylamine, and trimethylamine; and glucose.
proline, urea, dimethylamine, serine, 2013 [18] acetate, methanol [down arrow] valine, choline, arginine, creatinine, dimethylsulfone, Gln+ Gli, alanine, 1-dopa, dimethylglycine, citrate, lactate, lysine, uridine, methionine [up arrow] lactate + [down arrow] low cholesterol = Desmoulin et al.
to short-term 2, 4-D, dimethylamine and endosulfan exposure.
Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthase, produced by methylation of specific arginine residues of certain cellular proteins and released when hydrolysis of these proteins occurs.1,2 It is eliminated from the body by renal excretion (20%) and also metabolised (80%) by hydrolytic degradation to citrulline and dimethylamine (DMA) by the enzymatic action of dimethylarginine dimethylaminohydrolase (DDAH).3,4 Increased concentration of ADMA will compete with L-arginine to be transported into the endothelial cells leading to decreased synthesis of NO and endothelial dysfunction.5-7